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Common Stock and Preferred Stock - Antidilutive shares (Details) - shares
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Total shares excluded from net loss per share (in shares) 3,653,977 5,082,241
Warrants to purchase common stock    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Total shares excluded from net loss per share (in shares) 35,832 1,465,927
Options to purchase    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Total shares excluded from net loss per share (in shares) 3,618,145 3,616,314