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Net Loss Per Share (Details) - shares
shares in Thousands
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Options to purchase common stock    
Net Loss Per Share    
Securities excluded from the computation of diluted weighted-average shares outstanding 3,564,447 2,411,898
Nonvested restricted stock units    
Net Loss Per Share    
Securities excluded from the computation of diluted weighted-average shares outstanding 248,093 248,093
Employee stock option plan    
Net Loss Per Share    
Securities excluded from the computation of diluted weighted-average shares outstanding 92,892 93,040
Settlement of short-term debt    
Net Loss Per Share    
Securities excluded from the computation of diluted weighted-average shares outstanding 85,352 126,621
Nonvested restricted stock awards    
Net Loss Per Share    
Securities excluded from the computation of diluted weighted-average shares outstanding 10,586  
Warrants to purchase common stock    
Net Loss Per Share    
Securities excluded from the computation of diluted weighted-average shares outstanding   13,259