Condensed Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Condensed Consolidated Statements of Operations and Comprehensive Loss
Revenue	$ 803	$ 25
Operating expenses:
Research and development	10,342	3,079
General and administrative	6,468	4,168
Total operating expenses	16,810	7,247
Loss from operations	(16,007)	(7,222)
Other income (expense):
Interest income (expense), net	(372)	(281)
Other income (expense), net	71	(30)
Total other income (expense), net	(301)	(311)
Loss before income taxes	(16,308)	(7,533)
Benefit from income taxes	42	12
Net loss	$ (16,266)	$ (7,521)
Net loss per share - basic and diluted	$ (0.66)	$ (0.39)
Weighted average number of common shares used in net loss per share calculation--basic and diluted	24,818,224	19,284,653
Foreign currency translation adjustment	$ 62
Comprehensive loss	$ (16,204)	$ (7,521)