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Committments (Details)
$ in Thousands
1 Months Ended 12 Months Ended
May. 15, 2015
ft²
Mar. 31, 2013
USD ($)
Jan. 31, 2009
USD ($)
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Oct. 15, 2015
ft²
Sep. 09, 2015
ft²
Commitments              
Lease term of office lab       7 years      
Lessor Leasing Arrangements, Operating Leases, Term of Contract       7 years      
Future minimum lease payments              
2016       $ 2,399      
2017       1,092      
2018       644      
2019       655      
2020       666      
2021 and Thereafter       464      
Total       5,920      
Less: Future sublease payments to be received       (1,124)      
Net future lease payments       4,796      
Total rent expense       727 $ 366    
Boston office facility lease              
Commitments              
Additional Area of lease | ft² 3,000            
Term of lease 6 years            
Lease Monthly Rate       14      
Utrecht, The Netherlands              
Commitments              
Additional Area of lease | ft²             5,800
Lease Monthly Rate       25      
Zug, Switzerland              
Commitments              
Additional Area of lease | ft²           4,400  
Lease Monthly Rate       $ 17      
Moksha8 Pharmaceuticals Inc | License Agreements | Catalent Pharma Solutions, LLC | BOW015              
License Agreements              
Payments made as per agreement     $ 100        
Payments made upon exercise of its option     100        
Aggregate payments upon the achievement of certain development and regulatory milestones   $ 500 $ 700        
Milestone payments on clinical trial   $ 200          
Period of commercial sale of product       20 years      
Maximum percentage paid       1      
Period of notice for termination of agreement       60 days