Consolidated Statements of Operations and Comprehensive Loss - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014
Condensed Consolidated Statements of Operations and Comprehensive Loss
Revenue	$ 701	$ 4
Cost of revenues	(125)
Operating expenses:
Research and development	30,925	16,286
General and administrative	21,951	22,973
Total operating expenses	52,876	39,259
Loss from operations	(52,300)	(39,255)
Other income (expense):
Interest income (expense), net	(1,332)	(2,672)
Gain on sale of subsidiary	1,016
Change in fair value of warrant liability		(222)
Other income (expense), net	(116)	262
Total other income (expense), net	(432)	(2,632)
Loss before income taxes	(52,732)	(41,887)
Benefit from income taxes	544	43
Net loss	$ (52,188)	$ (41,844)
Net loss per share - basic and diluted	$ (2.29)	$ (6.81)
Weighted average number of common shares used in net loss per share calculation--basic and diluted	22,747,826	6,141,605
Foreign currency translation adjustment	$ (23)
Comprehensive loss	$ (52,211)	$ (41,844)