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Consolidated Statements of Operations and Comprehensive Loss (USD $)
In Thousands, except Share data, unless otherwise specified
12 Months Ended
Dec. 31, 2014
Dec. 31, 2013
Revenues:    
Revenue $ 4us-gaap_RoyaltyRevenue  
Operating expenses:    
Research and development 16,286us-gaap_ResearchAndDevelopmentExpense 9,659us-gaap_ResearchAndDevelopmentExpense
General and administrative 22,973us-gaap_GeneralAndAdministrativeExpense 4,809us-gaap_GeneralAndAdministrativeExpense
Total operating expenses 39,259us-gaap_OperatingExpenses 14,468us-gaap_OperatingExpenses
Loss from operations (39,255)us-gaap_OperatingIncomeLoss (14,468)us-gaap_OperatingIncomeLoss
Other income (expense):    
Interest expense, net (2,672)us-gaap_InterestIncomeExpenseNet (5,543)us-gaap_InterestIncomeExpenseNet
Change in fair value of warrant liability (222)us-gaap_FairValueAdjustmentOfWarrants (789)us-gaap_FairValueAdjustmentOfWarrants
Other income (expense), net 262us-gaap_OtherNonoperatingIncomeExpense 5us-gaap_OtherNonoperatingIncomeExpense
Total other income (expense), net (2,632)us-gaap_NonoperatingIncomeExpense (6,327)us-gaap_NonoperatingIncomeExpense
Loss before income taxes (41,887)us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest (20,795)us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest
Benefit (loss) from income taxes 43us-gaap_IncomeTaxExpenseBenefit  
Net loss (41,844)us-gaap_NetIncomeLoss (20,795)us-gaap_NetIncomeLoss
Net loss per share - basic and diluted $ (6.81)us-gaap_EarningsPerShareBasicAndDiluted $ (88.26)us-gaap_EarningsPerShareBasicAndDiluted
Weighted average number of common shares used in net loss per share calculation--basic and diluted 6,141,605us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted 235,603us-gaap_WeightedAverageNumberOfShareOutstandingBasicAndDiluted
Comprehensive loss $ (41,844)us-gaap_ComprehensiveIncomeNetOfTax $ (20,795)us-gaap_ComprehensiveIncomeNetOfTax