X0303 4 2010-02-02 0 0001069530 PAIN THERAPEUTICS INC PTIE 0001133806 BARBIER REMI 1 1 1 0 CEO and Chair of the Board Common Stock 2010-02-02 2010-02-02 4 G 0 28800 0 D 6321447 D Common Stock 2010-02-02 2010-02-02 4 G 0 9600 0 A 48375 I By family Common stock 2010-03-01 2010-03-01 4 S 0 29890 6.0457 D 6291557 D Common Stock 2010-03-02 2010-03-02 4 S 0 14667 6.1317 D 6276890 D This transaction is done in connection with a transaction by a member of the immediate familly of the reporting person. These transactions are exempt under Section 16b-3. This sale is made pursuant to a plan intended to comply with Rule 10b5-1(c). 29,890 shares of common stock were sold in twenty-four (24) lots at prices ranging from $5.92 to $6.13 per share. This sale is made pursuant to a plan intended to comply with Rule 10b-1(c). 14,667 shares of common stock were sold in fifteen (15) lots at prices ranging from $6.03 to $6.21 per share. /s/ Remi Barbier 2010-03-02