X0303 4 2010-02-01 0 0001069530 PAIN THERAPEUTICS INC PTIE 0001133806 BARBIER REMI 1 1 1 0 CEO, President, Chairman of Bd Common Stock 2010-02-01 2010-02-01 4 S 0 29800 5.304 D 6370447 D Common Stock 2010-02-02 2010-02-02 4 S 0 20200 5.343 D 6350247 D This sale is made pursuant to a plan intended to comply with Rule 10b5-1(c). 29,800 shares of common stock were sold in fourteen (14) lots at prices ranging from $5.23 to $5.36 per share. This sales is made pursuant to a plan intended to comply with Rule 10b5-1(c). 20,200 shars of common stock were sold in nine (9) lots at prices ranging from $5.31 to $5.39 per share. /s/Remi Barbier 2010-02-03