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Accrued Expenses (Detail) - USD ($)
$ in Thousands
9 Months Ended 12 Months Ended
Sep. 30, 2018
Dec. 31, 2017
Schedule of Accrued Liabilities [Line Items]    
Legal and accounting fees $ 91 $ 74
Accrued compensation 1,005 790
Accrued research and development costs and other 379 1,428
Total $ 1,475 $ 2,292