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Dilutive Shares Which Could Exist Pursuant to Exercise of Outstanding Stock Instruments and Which were not Included in Calculation (Detail) - shares
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Dilutive shares not included in calculation 15,032,827 11,417,832
Warrant    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Dilutive shares not included in calculation 8,908,586 5,470,995
Stock Options    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Dilutive shares not included in calculation 3,601,305 3,419,734
Contingently Issuable Shares    
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]    
Dilutive shares not included in calculation 2,522,936 2,527,103