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Agreement with Procaps S.a. and Research Grants - Additional Information (Detail) (USD $)
In Thousands, unless otherwise specified
12 Months Ended 150 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2012
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]        
Deferred revenue   $ 200    
Federal grants award 200   489 691
Federal grant received   $ 234 $ 255