Exhibit 99.1

              CERTIFICATION OF CHIEF EXECUTIVE OFFICER PURSUANT TO
                             18 U.S.C. SECTION 1350,
                             AS ADOPTED PURSUANT TO
                  SECTION 906 OF THE SARBANES-OXLEY ACT OF 2002

      In connection with the Quarterly Report of Pro-Pharmaceuticals, Inc. (the
"Company") on Form 10-QSB for the period ended September 30, 2002, as filed with
the Securities and Exchange Commission on the date hereof (the "Report"), the
undersigned officer of the Company does hereby certify, pursuant to 18 U.S.C.
Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of
2002, that:

(1)   The Report fully complies with the requirements of Section 13(a) or 15(d)
      of the Securities Exchange Act of 1934, as amended; and

(2)   The information contained in the Report fairly presents, in all material
      respects, the financial condition and results of operations of the
      Company.


                                    By: /S/ DAVID PLATT
                                        -----------------------------
                                        Name:  David Platt
                                        Title: President, Chief Executive
                                               Officer, Treasurer and Secretary
                                               (Principal Executive Officer)