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Stock-Based Compensation (Tables)
6 Months Ended
Jun. 30, 2023
Stock-Based Compensation [Abstract]  
Components of Stock-Based Compensation Expense

Following is the stock-based compensation expense related to common stock options, restricted common stock, common stock warrants and deferred stock units:
 
 
 
Three Months Ended
June 30,
   
Six Months Ended
June 30,
 
 
 
2023
   
2022
   
2023
   
2022
 
 
 
in thousands
 
Research and development
 
$
134
   
$
154
   
$
403
   
$
379
 
General and administrative
   
382
     
493
     
775
     
1,126
 
Total stock-based compensation expense
 
$
516
   
$
647
   
$
1,178
   
$
1,505
 
Stock Option Activity

The following table summarizes the stock option activity in the Company’s equity incentive plans, including non-plan grants to Company executives, from December 31, 2022 through June 30, 2023:
 
 
 
Shares
   
Weighted Average
Exercise Price
 
Outstanding, December 31, 2022
   
5,745,561
   
$
2.90
 
Granted
   
800,000
     
1.11
 
Exercised
   
   
 
Options forfeited/cancelled
   
(258,804
)
   
2.45
 
Outstanding, June 30, 2023
   
6,286,757
   
$
2.69
 
Weighted Average Assumptions Used to Determine Fair Value of Options Granted

The fair value of all other options granted is determined using the Black-Scholes option-pricing model. The following weighted average assumptions were used:
 
 
 
Six
Months Ended
June 30,
   
Six
Months Ended
June 30,
 
 
 
2023
   
2022
 
Risk-free interest rate
   
3.76
%
   
1.56
%
Expected life of the options
 
5.5 years
   
5.6 years
 
Expected volatility of the underlying stock
   
86
%
   
94
%
Expected dividend rate
   
0
%    
0
%