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Accrued Expenses and Other (Details) - USD ($)
Mar. 31, 2023
Dec. 31, 2022
Accrued Expenses and Other [Abstract]    
Legal and accounting fees $ 142,000 $ 65,000
Accrued compensation 386,000 973,000
Lease liability 42,000 40,000
Accrued research and development costs and other 8,410,000 7,980,000
Total $ 8,980,000 $ 9,058,000