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Stock-Based Compensation, Stock Option Activity (Details) - USD ($)
12 Months Ended
Dec. 31, 2021
Dec. 31, 2020
Stock Option Activity [Roll Forward]    
Outstanding at beginning of period (in shares) 3,987,575 3,000,256
Granted (in shares) 2,660,000 1,095,000
Forfeited/cancelled (in shares) (1,603,073) (23,057)
Exercised (in shares) (148,941) (84,624)
Outstanding at end of period (in shares) 4,895,561 3,987,575
Exercisable, end of period (in shares) 2,158,477  
Weighted Average Exercise Price [Abstract]    
Outstanding at beginning of period (in dollars per share) $ 4.29 $ 4.88
Granted (in dollars per share) 2.39 2.51
Forfeited/cancelled (in dollars per share) 5.31 1.80
Exercised (in dollars per share) 2.35 2.61
Outstanding at beginning of period (in dollars per share) 3.14 4.29
Exercisable, end of period (in dollars per share) $ 4.09  
Weighted Average Remaining Contractual Life [Abstract]    
Outstanding end of the period 7 years 11 months 8 days  
Exercisable, end of the period 6 years 3 months 14 days  
Aggregate Intrinsic Value [Abstract]    
Outstanding at end of period $ 246,000  
Exercisable, end of period $ 169,000  
Share-based Payment Arrangement, Nonvested Award, Cost Not yet Recognized [Abstract]    
Common stock price (in dollars per share) $ 2.07  
Weighted-average grant-date fair values of options granted (in dollars per share) $ 1.78 $ 1.92
Unvested option (in shares) 2,737,084 651,667
Unrecognized compensation cost $ 3,654,000  
Unrecognized compensation cost, recognition period 2 years 25 days  
Intrinsic value of stock options $ 532,447 $ 39,792
Options vested (in shares) 284,583 850,833
Total fair value of options vested $ 514,287 $ 2,531,758