Nature of Business, Basis of Presentation and Liquidity (Details) - USD ($)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Nature of Business, Basis of Presentation and Liquidity [Abstract]
Cash and cash equivalents	$ 39,648,000	$ 27,142,000
Minimum [Member]
Nature of Business, Basis of Presentation and Liquidity [Abstract]
Additional estimated costs of clinical trial and general overhead	45,000,000
Maximum [Member]
Nature of Business, Basis of Presentation and Liquidity [Abstract]
Additional estimated costs of clinical trial and general overhead	$ 50,000,000