The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ARM HOLDINGS PLC SPONSORED ADR 042068205   16,656,050 215,000 SH   DFND   0 0 215,000
IMMUNOVANT INC COM 45258J102   2,738 65 SH   DFND   0 0 65
10X GENOMICS INC CL A COM 88025U109   18,579 332 SH   DFND   0 0 332
4D MOLECULAR THERAPEUTICS IN COM 35104E100   33,348 1,646 SH   DFND   0 0 1,646
ABBOTT LABS COM 002824100   60,098 546 SH   DFND   0 0 546
ABBVIE INC COM 00287Y109   1,200,088 7,744 SH   DFND   7,315 0 429
ACUITY BRANDS INC COM 00508Y102   5,735 28 SH   DFND   0 0 28
ADVANCED DRAIN SYS INC DEL COM 00790R104   6,469 46 SH   DFND   0 0 46
ADVANCED MICRO DEVICES INC COM 007903107   16,819,481 114,100 SH   DFND   0 0 114,100
AGILENT TECHNOLOGIES INC COM 00846U101   134,998 971 SH   DFND   0 0 971
AIR PRODS & CHEMS INC COM 009158106   96,378 352 SH   DFND   0 0 352
ALCOA CORP COM 013872106   9,052,100 262,000 SH   DFND   0 0 262,000
ALIBABA GROUP HLDG LTD SPONSORED ADS 01609W102   1,419,053 18,372 SH   DFND   0 0 18,372
ALLOGENE THERAPEUTICS INC COM 019770106   29,410 9,162 SH   DFND   0 0 9,162
ALNYLAM PHARMACEUTICALS INC COM 02043Q107   132,647 693 SH   DFND   0 0 693
ALPHABET INC CAP STK CL A 02079K305   11,119,184 79,599 SH   DFND   4,894 0 74,705
ALPHABET INC CAP STK CL C 02079K107   2,701,294 19,121 SH   DFND   0 0 19,121
AMAZON COM INC COM 023135106   44,118,362 290,367 SH   DFND   20,068 0 270,299
AMBARELLA INC SHS G037AX101   25,190 411 SH   DFND   0 0 411
AMBEV SA SPONSORED ADR 02319V103   5,979,642 2,143,241 SH   DFND   0 0 2,143,241
AMBEV SA SPONSORED ADR 02319V103   388,647 139,300 SH   DFND 1 0 0 139,300
AMERICA MOVIL SAB DE CV SPONSORED ADR 02390A101   800,241 43,291 SH   DFND   0 0 43,291
AMERICA MOVIL SAB DE CV SPONSORED ADR 02390A101   20,855,296 1,128,218 SH   DFND 1 199,615 0 928,603
AMERICAN HOMES 4 RENT CL A 02665T306   381,150 10,500 SH   DFND   0 0 10,500
AMERICAN WTR WKS CO INC NEW COM 030420103   26,794 203 SH   DFND   0 0 203
AMGEN INC COM 031162100   67,109 233 SH   DFND   0 0 233
ANTHEM INC COM 036752103   35,367 75 SH   DFND   0 0 75
APARTMENT INVT & MGMT CO CL A 03748R747   535,458 67,100 SH   DFND   0 0 67,100
APPLIED MATLS INC COM 038222105   33,548 207 SH   DFND   0 0 207
ARCOS DORADOS HOLDINGS INC SHS CLASS -A - G0457F107   6,922,002 545,469 SH   DFND   0 0 545,469
ARMSTRONG WORLD INDS INC NEW COM 04247X102   5,801 59 SH   DFND   0 0 59
ARROWHEAD PHARMACEUTICALS IN COM 04280A100   4,376 143 SH   DFND   0 0 143
ASANA INC CL A 04342Y104   23,021 1,211 SH   DFND   0 0 1,211
ASHLAND GLOBAL HLDGS INC COM 044186104   7,672 91 SH   DFND   0 0 91
ASML HOLDING N V N Y REGISTRY SHS N07059210   8,639,490 11,400 SH   DFND   0 0 11,400
ASTRAZENECA PLC SPONSORED ADR 046353108   1,102,452 16,369 SH   DFND   0 0 16,369
AT&T INC PUT 00206R952   5 500 SH Call DFND   0 0 500
AURORA INNOVATION INC COM 051774107   41,498 9,496 SH   DFND   0 0 9,496
AVALONBAY CMNTYS INC COM 053484101   805,800 4,250 SH   DFND   0 0 4,250
AVIDITY BIOSCIENCES INC COM 05370A108   26,770 2,958 SH   DFND   0 0 2,958
AVIS BUDGET GROUP COM 053774105   7,445 42 SH   DFND   0 0 42
BALL CORP COM 058498106   12,367 215 SH   DFND   0 0 215
BALLARD PWR SYS INC NEW COM 058586108   110,408 29,840 SH   DFND   0 0 29,840
BANCO BRADESCO S A SP ADR PFD NEW 059460303   53,612,306 15,102,058 SH   DFND   0 0 15,102,058
BANCO BRADESCO S A SP ADR PFD NEW 059460303   78,079,588 21,994,250 SH   DFND 1 1,821,213 0 20,173,037
BANCO DE CHILE SPONSORED ADS 059520106   72,725 3,151 SH   DFND   0 0 3,151
BANCO DE CHILE SPONSORED ADS 059520106   2,035,518 88,194 SH   DFND 1 20,650 0 67,544
BANCO MACRO SA SPON ADR B 05961W105   83,230 2,900 SH   DFND   0 0 2,900
BANCO MACRO SA SPON ADR B 05961W105   83,230 2,900 SH   DFND 1 2,900 0 0
BANCO SANTANDER BRASIL S A ADS REP 1 UNIT 05967A107   950 145 SH   DFND   0 0 145
BANCO SANTANDER CHILE NEW SP ADR REP COM 05965X109   12,435 638 SH   DFND   0 0 638
BANCO SANTANDER CHILE NEW SP ADR REP COM 05965X109   321,994 16,521 SH   DFND 1 3,845 0 12,676
BARRICK GOLD CORP COM 067901108   202,789 11,210 SH   DFND   0 0 11,210
BARRICK GOLD CORP COM 067901108   202,789 11,210 SH   DFND 1 11,210 0 0
BEAM THERAPEUTICS INC COM 07373V105   6,424 236 SH   DFND   0 0 236
BERKSHIRE HATHAWAY INC DEL CL B NEW 084670702   715 2 SH   DFND   0 0 2
BEST BUY INC COM 086516101   5,625,357 71,862 SH   DFND   71,862 0 0
BIGCOMMERCE HLDGS INC COM SER 1 08975P108   24,812 2,550 SH   DFND   0 0 2,550
BILIBILI INC SPONS ADS REP Z 090040106   24,377 2,003 SH   DFND   0 0 2,003
BIO RAD LABS INC CL A 090572207   12,270 38 SH   DFND   0 0 38
BIO TECHNE CORP COM 09073M104   46,065 597 SH   DFND   0 0 597
BIOGEN INC COM 09062X103   69,350 268 SH   DFND   0 0 268
BIOMARIN PHARMACEUTICAL INC COM 09061G101   64,312 667 SH   DFND   0 0 667
BLOOM ENERGY CORP COM CL A 093712107   134,917 9,116 SH   DFND   0 0 9,116
BLUEBIRD BIO INC COM 09609G100   6,718 4,868 SH   DFND   0 0 4,868
BLUEPRINT MEDICINES CORP COM 09627Y109   7,287 79 SH   DFND   0 0 79
BOOKING HOLDINGS INC COM 09857L108   39,019 11 SH   DFND   0 0 11
BOSTON PROPERTIES INC COM 101121101   13,192 188 SH   DFND   0 0 188
BRISTOL MYERS SQUIBB CO COM 110122108   122,528 2,388 SH   DFND   0 0 2,388
BROADCOM INC COM 11135F101   9,412,220 8,432 SH   DFND   0 0 8,432
BROOKS AUTOMATION INC COM 114340102   3,518 54 SH   DFND   0 0 54
BRUKER CORP COM 116794108   13,888 189 SH   DFND   0 0 189
BUTTERFLY NETWORK INC COM CL A 124155102   16,203 15,003 SH   DFND   0 0 15,003
C3 AI INC CL A 12468P104   23,140 806 SH   DFND   0 0 806
CAPRI HOLDINGS LIMITED SHS G1890L107   2,824,640 56,000 SH   DFND   0 0 56,000
CARLISLE COS INC COM 142339100   6,249 20 SH   DFND   0 0 20
CATALENT INC COM 148806102   23,319 519 SH   DFND   0 0 519
CEMEX SAB DE CV SPON ADR NEW 151290889   35,207,949 4,714,463 SH   DFND   0 0 4,714,463
CEMEX SAB DE CV SPON ADR NEW 151290889   61,296,113 8,207,756 SH   DFND 1 837,224 0 7,370,532
CENTRAIS ELETRICAS BRASILEIR SPONSORED ADR 15234Q207   10,549,587 1,223,850 SH   DFND   0 0 1,223,850
CEREVEL THERAPEUTICS HLDNG I COM 15678U128   3,901 92 SH   DFND   0 0 92
CHARLES RIV LABS INTL INC COM 159864107   13,711 58 SH   DFND   0 0 58
CHART INDS INC COM PAR $0.01 16115Q308   105,383 773 SH   DFND   0 0 773
CHEMOURS CO COM 163851108   92,412 2,930 SH   DFND   0 0 2,930
CI&T INC COM CL A G21307106   2,179,486 414,351 SH   DFND   0 0 414,351
CISCO SYS INC COM 17275R102   1,427,847 28,263 SH   DFND   28,263 0 0
CLEAN HARBORS INC COM 184496107   9,075 52 SH   DFND   0 0 52
CLEARWAY ENERGY INC CL A 18539C105   5,397 211 SH   DFND   0 0 211
CLEARWAY ENERGY INC CL C 18539C204   5,486 200 SH   DFND   0 0 200
COCA COLA CO COM 191216100   5,357,562 90,914 SH   DFND   17,580 0 73,334
COCA COLA FEMSA S A B DE C V SPON ADR REP L 191241108   16,807,877 185,567 SH   DFND   0 0 185,567
COCA COLA FEMSA S A B DE C V SPON ADR REP L 191241108   27,889,824 307,917 SH   DFND 1 28,017 0 279,900
COINBASE GLOBAL INC COM CL A 19260Q107   179,833 1,034 SH   DFND   860 0 174
COLGATE PALMOLIVE CO COM 194162103   27,181 341 SH   DFND   0 0 341
COMCAST CORP NEW CL A 20030N101   51,524 1,175 SH   DFND   0 0 1,175
COMPANHIA DE SANEAMENTO BASI SPONSORED ADR 20441A102   1,310,404 86,041 SH   DFND   0 0 86,041
COMPANHIA SIDERURGICA NACION SPONSORED ADR 20440W105   891,022 222,200 SH   DFND   0 0 222,200
COPA HOLDINGS SA CL A P31076105   1,882,655 17,567 SH   DFND   0 0 17,567
CORVEL CORP COM 221006109   2,472 10 SH   DFND   0 0 10
COSAN LTD SHS A 22113B103   10,051,246 641,842 SH   DFND   641,842 0 0
COSTAR GROUP INC COM 22160N109   5,156 59 SH   DFND   0 0 59
COUCHBASE INC COM 22207T101   26,506 1,177 SH   DFND   0 0 1,177
CREDICORP LTD COM G2519Y108   40,302,395 280,725 SH   DFND   0 0 280,725
CREDICORP LTD COM G2519Y108   71,534,185 498,269 SH   DFND 1 49,765 0 448,504
CRISPR THERAPEUTICS AG NAMEN AKT H17182108   93,775 1,498 SH   DFND   0 0 1,498
CROWDSTRIKE HLDGS INC CL A 22788C105   5,634,860 22,000 SH   DFND   0 0 22,000
CSX CORP COM 126408103   33,110 955 SH   DFND   0 0 955
CUMMINS INC COM 231021106   100,619 420 SH   DFND   0 0 420
DARLING INGREDIENTS INC COM 237266101   13,307 267 SH   DFND   0 0 267
DBX ETF TR XTRACK HRVST CSI 233051879   357,000 15,000 SH   DFND   0 0 15,000
DEERE & CO COM 244199105   2,359,233 5,900 SH   DFND   0 0 5,900
DELTA AIR LINES INC DEL COM NEW 247361702   3,656,700 90,000 SH   DFND   0 0 90,000
DISNEY WALT CO COM DISNEY 254687106   695,323 7,701 SH   DFND   2,027 0 5,674
DOLLAR GEN CORP NEW COM 256677105   4,464,054 32,836 SH   DFND   0 0 32,836
EATON CORP PLC SHS G29183103   45,033 187 SH   DFND   0 0 187
EDITAS MEDICINE INC COM 28106W103   21,435 2,116 SH   DFND   0 0 2,116
EDWARDS LIFESCIENCES CORP COM 28176E108   68,930 904 SH   DFND   0 0 904
EHANG HLDGS LTD ADS 26853E102   23,150 1,378 SH   DFND   0 0 1,378
ELECTRONIC ARTS INC COM 285512109   5,062 37 SH   DFND   0 0 37
EMBRAER S A SP ADR REP 4 COM 29082A107   17,174,842 977,460 SH   DFND   0 0 977,460
EMBRAER S A SP ADR REP 4 COM 29082A107   25,889,424 1,473,427 SH   DFND 1 128,236 0 1,345,191
ENPHASE ENERGY INC COM 29355A107   65,277 494 SH   DFND   250 0 244
EOS ENERGY ENTERPRISES INC COM CL A 29415C101   23,243 21,324 SH   DFND   0 0 21,324
EQUINIX INC COM PAR $0.001 29444U700   82,150 102 SH   DFND   0 0 102
EQUITY RESIDENTIAL SH BEN INT 29476L107   825,000 13,200 SH   DFND   0 0 13,200
ESSENTIAL UTILS INC COM 29670G102   5,229 140 SH   DFND   0 0 140
ESSEX PPTY TR INC COM 297178105   581,325 2,300 SH   DFND   0 0 2,300
ETF MANAGERS TR PRIME MOBILE PAY 26924G409   515,900 11,000 SH   DFND   0 0 11,000
EXACT SCIENCES CORP COM 30063P105   93,363 1,262 SH   DFND   0 0 1,262
EXELIXIS INC COM 30161Q104   11,443 477 SH   DFND   0 0 477
FACEBOOK INC CL A 30303M102   23,205,618 65,560 SH   DFND   951 0 64,609
FASTLY INC CL A 31188V100   24,689 1,387 SH   DFND   0 0 1,387
FEDEX CORP COM 31428X106   8,854 35 SH   DFND   0 0 35
FIRST SOLAR INC COM 336433107   33,595 195 SH   DFND   0 0 195
FISERV INC COM 337738108   24,044 181 SH   DFND   0 0 181
FISKER INC CL A COM STK 33813J106   29,111 16,635 SH   DFND   0 0 16,635
FOMENTO ECONOMICO MEXICANO S SPON ADR UNITS 344419106   87,812,347 704,843 SH   DFND   0 0 704,843
FOMENTO ECONOMICO MEXICANO S SPON ADR UNITS 344419106   161,731,430 1,298,169 SH   DFND 1 137,705 0 1,160,464
FORTUNE BRANDS HOME & SEC IN COM 34964C106   5,558 73 SH   DFND   0 0 73
FRANKLIN TEMPLETON ETF TR FTSE CANADA 35473P827   1,724,026 51,866 SH   DFND   0 0 51,866
FRANKLIN TEMPLETON ETF TR FTSE JAPAN ETF 35473P744   5,226,041 186,711 SH   DFND   0 0 186,711
FUELCELL ENERGY INC COM 35952H601   128,322 80,201 SH   DFND   0 0 80,201
GENERAL ELECTRIC CO COM 369604301   1,801,453 14,041 SH   DFND   0 0 14,041
GERDAU SA SPON ADR REP PFD 373737105   8,835,895 1,821,834 SH   DFND   0 0 1,821,834
GERDAU SA SPON ADR REP PFD 373737105   5,417,178 1,116,944 SH   DFND 1 245,669 0 871,275
GILEAD SCIENCES INC COM 375558103   179,275 2,213 SH   DFND   695 0 1,518
GINKGO BIOWORKS HOLDINGS INC CL A SHS 37611X100   30,493 18,043 SH   DFND   0 0 18,043
GLOBAL X FDS GLOBAL X URANIUM 37954Y871   17,110,288 617,923 SH   DFND   0 0 617,923
GLOBAL X FDS LITHIUM BTRY ETF 37954Y855   46,457 912 SH   DFND   0 0 912
GLOBANT S A COM L44385109   190,384 800 SH   DFND   0 0 800
GLOBANT S A COM L44385109   190,384 800 SH   DFND 1 800 0 0
GRAPHIC PACKAGING HLDG CO COM 388689101   496,000 20,000 SH   DFND   0 0 20,000
GRUPO AEROPORTUARIO DEL SURE SPON ADR SER B 40051E202   20,310,786 71,709 SH   DFND   0 0 71,709
GRUPO AEROPORTUARIO DEL SURE SPON ADR SER B 40051E202   37,368,289 131,932 SH   DFND 1 13,901 0 118,031
GRUPO AEROPUERTO DEL PACIFIC SPON ADR B 400506101   4,630,959 26,966 SH   DFND   0 0 26,966
GRUPO AEROPUERTO DEL PACIFIC SPON ADR B 400506101   17,466,645 101,708 SH   DFND 1 18,230 0 83,478
GRUPO FINANCIERO GALICIA S A SP ADR 10 SH B 399909100   1,736,000 100,000 SH   DFND   0 0 100,000
GRUPO TELEVISA SA SPON ADR REP ORD 40049J206   41,530 13,182 SH   DFND   0 0 13,182
GRUPO TELEVISA SA SPON ADR REP ORD 40049J206   41,530 13,182 SH   DFND 1 0 0 13,182
GUARDANT HEALTH INC COM 40131M109   77,390 2,861 SH   DFND   0 0 2,861
HDFC BANK LTD ADR REPS 3 SHS 40415F101   153,682 2,290 SH   DFND   0 0 2,290
HDFC BANK LTD ADR REPS 3 SHS 40415F101   153,682 2,290 SH   DFND 1 2,290 0 0
HEWLETT PACKARD ENTERPRISE C COM 42824C109   46,287 2,726 SH   DFND   0 0 2,726
HEXCEL CORP NEW COM 428291108   7,744 105 SH   DFND   0 0 105
HOLOGIC INC COM 436440101   35,082 491 SH   DFND   0 0 491
HYSTER YALE MATLS HANDLING I CL A 449172105   49,441 795 SH   DFND   0 0 795
ICICI BK LTD ADR 45104G104   458,920 19,250 SH   DFND   0 0 19,250
ICICI BK LTD ADR 45104G104   458,920 19,250 SH   DFND 1 19,250 0 0
ILLUMINA INC COM 452327109   510,856 3,617 SH   DFND   0 0 3,617
IMMUNOGEN INC COM 45253H101   26,448 892 SH   DFND   0 0 892
INCYTE CORP COM 45337C102   71,141 1,133 SH   DFND   0 0 1,133
INDIE SEMICONDUCTOR INC CLASS A COM 45569U101   25,879 3,191 SH   DFND   0 0 3,191
INFOSYS LTD SPONSORED ADR 456788108   255,261 13,888 SH   DFND   0 0 13,888
INNOVIZ TECHNOLOGIES LTD SHS M5R635108   33,153 13,104 SH   DFND   0 0 13,104
INTEGRA LIFESCIENCES HLDGS C COM NEW 457985208   4,181 96 SH   DFND   0 0 96
INTELLIA THERAPEUTICS INC COM 45826J105   97,781 3,207 SH   DFND   0 0 3,207
INTUITIVE SURGICAL INC COM NEW 46120E602   68,147 202 SH   DFND   0 0 202
INVESCO ACTIVELY MANAGD ETF ACTIVE US REAL 46090A101   2,129,504 5,200 SH   DFND   0 0 5,200
INVESCO DB MLTI SECTR CMMTY AGRICULTURE FD 46140H106   1,663,348 80,200 SH   DFND   80,200 0 0
INVITATION HOMES INC COM 46187W107   393,845 11,350 SH   DFND   0 0 11,350
IONIS PHARMACEUTICALS INC COM 462222100   72,293 1,429 SH   DFND   0 0 1,429
IQVIA HLDGS INC COM 46266C105   58,308 252 SH   DFND   0 0 252
ISHARES INC MSCI BRAZIL ETF 464286400   15,490,776 443,100 SH   DFND   0 0 443,100
ISHARES INC MSCI JPN ETF NEW 46434G822   314,350 4,901 SH   DFND   0 0 4,901
ISHARES INC MSCI JPN ETF NEW 46434G822   43,148,453 672,723 SH   DFND 1 672,723 0 0
ISHARES INC MSCI TAIWAN ETF 46434G772   322,210 7,000 SH   DFND   0 0 7,000
ISHARES INC MSCI PAC JP ETF 464286665   295,188 6,800 SH   DFND   0 0 6,800
ISHARES INC MSCI STH KOR ETF 464286772   659,800 10,000 SH   DFND   0 0 10,000
ISHARES INC CORE MSCI EMKT 46434G103   546,264 10,800 SH   DFND   0 0 10,800
ISHARES SILVER TRUST ISHARES 46428Q109   55,016 2,526 SH   DFND   0 0 2,526
ISHARES TR CALL 464287904   196,418 2,000 SH Call DFND   0 0 2,000
ISHARES TR MSCI EMG MKT ETF 464287234   11,666,449 290,138 SH   DFND 1 290,138 0 0
ISHARES TR RUSSELL 2000 ETF 464287655   16,715,530 83,282 SH   DFND   0 0 83,282
ISHARES TR IBOXX INV CP ETF 464287242   8,299 75 SH   DFND 1 75 0 0
ISHARES TR S&P 500 VAL ETF 464287408   4,695,030 27,000 SH   DFND   0 0 27,000
ISHARES TR 10-20 YR TRS ETF 464288653   115,248,941 1,064,557 SH   DFND 1 1,064,557 0 0
ISHARES TR US TREAS BD ETF 46429B267   102,846,966 4,463,844 SH   DFND 1 4,463,844 0 0
ISHARES TR NASDAQ BIOTECH 464287556   29,220,656 215,095 SH   DFND   0 0 215,095
ISHARES TR NA TEC SFTWR ETF 464287515   1,633,360 4,000 SH   DFND   0 0 4,000
ISHARES TR BARCLAYS 7 10 YR 464287440   2,409,636 13,688 SH   DFND 1 13,688 0 0
ISHARES TR U.S. REAL ES ETF 464287739   1,413,656 15,465 SH   DFND   0 0 15,465
ISHARES TR CORE S&P500 ETF 464287200   2,711,302 5,401 SH   DFND 1 5,401 0 0
ITAU UNIBANCO HLDG S A SPON ADR REP PFD 465562106   58,918,375 8,826,300 SH   DFND   0 0 8,826,300
ITAU UNIBANCO HLDG S A SPON ADR REP PFD 465562106   145,752,449 21,834,527 SH   DFND 1 2,282,495 0 19,552,032
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   63,468 516 SH   DFND   0 0 516
JOHNSON & JOHNSON COM 478160104   502,822 3,208 SH   DFND   2,807 0 401
JOHNSON CTLS INTL PLC SHS G51502105   16,024 278 SH   DFND   0 0 278
JPMORGAN CHASE & CO COM 46625H100   6,024,772 35,419 SH   DFND   0 0 35,419
JUMIA TECHNOLOGIES AG SPONSORED ADS 48138M105   17,445 4,942 SH   DFND   0 0 4,942
KEURIG DR PEPPER INC COM 49271V100   6,612,920 198,467 SH   DFND   0 0 198,467
KRAFT HEINZ CO COM 500754106   4,696 127 SH   DFND   0 0 127
KRANESHARES TR CALL 500767906   16,700 3,000 SH Call DFND   0 0 3,000
KROGER CO COM 501044101   10,833 237 SH   DFND   0 0 237
LAM RESEARCH CORP COM 512807108   4,594,968 5,819 SH   DFND   0 0 5,819
LANZATECH GLOBAL INC COM 51655R101   18,183 3,615 SH   DFND   0 0 3,615
LI AUTO INC SPONSORED ADS 50202M102   1,657,350 45,000 SH   DFND   0 0 45,000
LILLY ELI & CO COM 532457108   62,372 107 SH   DFND   0 0 107
LINDE PLC COM G5494J103   95,695 233 SH   DFND   0 0 233
LISTED FD TR ROUNDHILL BALL 53656F417   393,642 34,200 SH   DFND   0 0 34,200
LOCKHEED MARTIN CORP COM 539830109   446,718 990 SH   DFND   0 0 990
LOUISIANA PAC CORP COM 546347105   5,808 82 SH   DFND   0 0 82
LOWES COS INC COM 548661107   4,340,615 19,504 SH   DFND   0 0 19,504
LUCID GROUP INC COM 549498103   29,752 7,067 SH   DFND   0 0 7,067
LUMINAR TECHNOLOGIES INC COM CL A 550424105   30,519 9,056 SH   DFND   0 0 9,056
LUXFER HOLDINGS PLC SHS G5698W116   34,365 3,844 SH   DFND   0 0 3,844
LVMH MOET HENNESSY LOUIS VUITTON AS COM 502441306   6,964,280 43,000 SH   DFND   0 0 43,000
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109   134,363 2,860 SH   DFND   0 0 2,860
MAKEMYTRIP LIMITED MAURITIUS SHS V5633W109   134,363 2,860 SH   DFND 1 2,860 0 0
MASCO CORP COM 574599106   7,100 106 SH   DFND   0 0 106
MASTERCARD INCORPORATED CL A 57636Q104   405,004 950 SH   DFND   0 0 950
MATTERPORT INC CALL 577096900   132,721 6,000 SH Call DFND   0 0 6,000
MATTERPORT INC COM CL A 577096100   4,195,744 1,559,756 SH   DFND   1,559,756 0 0
MCDONALDS CORP COM 580135101   64,936 219 SH   DFND   0 0 219
MEDPACE HLDGS INC COM 58506Q109   28,201 92 SH   DFND   0 0 92
MERCADOLIBRE INC COM 58733R102   59,343,798 37,632 SH   DFND   0 0 37,632
MERCADOLIBRE INC COM 58733R102   19,373,588 12,832 SH   DFND 1 1,278 0 11,554
MERCK & CO INC COM 58933Y105   64,758 594 SH   DFND   0 0 594
METTLER TOLEDO INTERNATIONAL COM 592688105   69,139 57 SH   DFND   0 0 57
MICRON TECHNOLOGY INC COM 595112103   13,950,188 163,466 SH   DFND   0 0 163,466
MICROSOFT CORP COM 594918104   57,755,984 153,590 SH   DFND   9,061 0 144,529
MICROVISION INC DEL COM NEW 594960304   22,477 8,450 SH   DFND   0 0 8,450
MID AMER APT CMNTYS INC COM 59522J103   819,300 6,000 SH   DFND   0 0 6,000
MIRATI THERAPEUTICS INC COM 60468T105   7,931 135 SH   DFND   0 0 135
MODERNA INC COM 60770K107   146,987 1,478 SH   DFND   0 0 1,478
MONDELEZ INTL INC CL A 609207105   44,182 610 SH   DFND   0 0 610
NANO DIMENSION LTD SPONSORD ADS NEW 63008G203   23,820 9,925 SH   DFND   0 0 9,925
NATERA INC COM 632307104   26,559 424 SH   DFND   0 0 424
NATURA &CO HLDG S A ADS 63884N108   1,500,012 219,300 SH   DFND   0 0 219,300
NEOGENOMICS INC COM NEW 64049M209   6,828 422 SH   DFND   0 0 422
NETFLIX INC COM 64110L106   11,021,503 22,637 SH   DFND   3,281 0 19,356
NEW ORIENTAL ED & TECH GRP I SPON ADR 647581206   131,171 1,790 SH   DFND   0 0 1,790
NEW ORIENTAL ED & TECH GRP I SPON ADR 647581206   131,171 1,790 SH   DFND 1 1,790 0 0
NEWMONT MINING CORP COM 651639106   661,247 15,976 SH   DFND   15,976 0 0
NEXTERA ENERGY INC COM 65339F101   7,425,526 122,251 SH   DFND   122,251 0 0
NIKE INC CL B 654106103   91,090 839 SH   DFND   228 0 611
NIKOLA CORP COM 654110105   99,352 113,571 SH   DFND   0 0 113,571
NIO INC SPON ADS 62914V106   1,697,400 180,000 SH   DFND   0 0 180,000
NORFOLK SOUTHERN CORP COM 655844108   24,111 102 SH   DFND   0 0 102
NORTHROP GRUMMAN CORP COM 666807102   419,112 900 SH   DFND   0 0 900
NU HLDGS LTD ORD SHS CL A G6683N103   22,641,290 2,718,042 SH   DFND   0 0 2,718,042
NU HLDGS LTD ORD SHS CL A G6683N103   12,280,086 1,474,200 SH   DFND 1 120,300 0 1,353,900
NUTANIX INC CL A 67059N108   22,605 474 SH   DFND   0 0 474
NVIDIA CORP COM 67066G104   37,968,517 76,670 SH   DFND   1,048 0 75,622
NXP SEMICONDUCTORS N V COM N6596X109   9,255,203 40,054 SH   DFND   0 0 40,054
OCCIDENTAL PETE CORP DEL COM 674599105   161,259 2,689 SH   DFND   0 0 2,689
OLIN CORP COM PAR $1 680665205   114,536 2,123 SH   DFND   0 0 2,123
OMEGA HEALTHCARE INVS INC COM 681936100   11,252 367 SH   DFND   0 0 367
ORACLE CORP COM 68389X105   4,333,489 41,103 SH   DFND   0 0 41,103
OUSTER INC COM 68989M103   20,180 2,631 SH   DFND   0 0 2,631
OWENS CORNING NEW COM 690742101   5,485 37 SH   DFND   0 0 37
PACIFIC BIOSCIENCES CALIF IN COM 69404D108   8,809 898 SH   DFND   0 0 898
PAGSEGURO DIGITAL LTD COM CL A G68707101   2,965,123 232,924 SH   DFND   0 0 232,924
PAMPA ENERGIA S A SPONS ADR LVL I 697660207   2,432,500 50,000 SH   DFND   0 0 50,000
PAYPAL HLDGS INC COM 70450Y103   525,915 8,564 SH   DFND   1,036 0 7,528
PENTAIR PLC SHS G7S00T104   5,599 77 SH   DFND   0 0 77
PEPSICO INC COM 713448108   56,727 334 SH   DFND   0 0 334
PERKINELMER INC COM 714046109   95,646 875 SH   DFND   0 0 875
PETROLEO BRASILEIRO SA PETRO SP ADR NON VTG 71654V101   40,774,395 2,658,044 SH   DFND   551,286 0 2,106,758
PETROLEO BRASILEIRO SA PETRO SP ADR NON VTG 71654V101   70,555,241 4,599,429 SH   DFND 1 740,498 0 3,858,931
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408   88,642,303 5,519,446 SH   DFND   4,466,048 0 1,053,398
PETROLEO BRASILEIRO SA PETRO SPONSORED ADR 71654V408   41,829,812 2,604,596 SH   DFND 1 400,065 0 2,204,531
PINDUODUO INC SPONSORED ADS 722304102   555,978 3,800 SH   DFND   0 0 3,800
PINDUODUO INC SPONSORED ADS 722304102   555,978 3,800 SH   DFND 1 3,800 0 0
PLANET LABS PBC COM CL A 72703X106   19,881 8,049 SH   DFND   0 0 8,049
PLUG POWER INC COM NEW 72919P202   76,446 16,988 SH   DFND   0 0 16,988
PROCTER AND GAMBLE CO COM 742718109   51,289 350 SH   DFND   0 0 350
PUBLIC SVC ENTERPRISE GROUP COM 744573106   1,095,074 17,908 SH   DFND   17,908 0 0
QUALCOMM INC COM 747525103   7,584,720 52,000 SH   DFND   0 0 52,000
QUEST DIAGNOSTICS INC COM 74834L100   17,924 130 SH   DFND   0 0 130
QUIDELORTHO CORP COM 219798105   7,370 100 SH   DFND   0 0 100
RAYONIER INC COM 754907103   7,918 237 SH   DFND   0 0 237
RECURSION PHARMACEUTICALS IN CL A 75629V104   31,167 3,161 SH   DFND   0 0 3,161
REGENERON PHARMACEUTICALS COM 75886F107   126,474 144 SH   DFND   0 0 144
REKOR SYSTEMS INC COM 759419104   21,042 6,319 SH   DFND   0 0 6,319
RELIANCE STEEL & ALUMINUM CO COM 759509102   241,250 3,860 SH   DFND   0 0 3,860
REPLIGEN CORP COM 759916109   12,946 72 SH   DFND   0 0 72
REPUBLIC SVCS INC COM 760759100   35,456 215 SH   DFND   0 0 215
REVOLUTION MEDICINES INC COM 76155X100   9,292 324 SH   DFND   0 0 324
RIDGEBIO PHARMA INC COM COM 10806X102   10,496 260 SH   DFND   0 0 260
ROBINHOOD MKTS INC COM CL A 770700102   26,512 2,081 SH   DFND   0 0 2,081
ROBLOX CORP CL A 771049103   1,255,837 27,468 SH   DFND   27,468 0 0
ROCKWELL AUTOMATION INC COM 773903109   15,551,322 50,088 SH   DFND   0 0 50,088
ROIVANT SCIENCES LTD SHS G76279101   26,873 2,393 SH   DFND   0 0 2,393
ROSS STORES INC COM 778296103   2,173,553 15,706 SH   DFND   0 0 15,706
RUMBLE INC COM CL A 78137L105   22,944 5,110 SH   DFND   0 0 5,110
S&P GLOBAL INC COM 78409V104   3,229,850 7,310 SH   DFND   0 0 7,310
SAREPTA THERAPEUTICS INC COM 803607100   16,297 169 SH   DFND   0 0 169
SEA LTD ADR 81141R100   47,223 1,166 SH   DFND   0 0 1,166
SELECT SECTOR SPDR TR TECHNOLOGY 81369Y803   1,482,096 7,700 SH   DFND   0 0 7,700
SELECT SECTOR SPDR TR SBI CONS DISCR 81369Y407   634,954 3,551 SH   DFND   0 0 3,551
SENTINELONE INC CL A 81730H109   27,660 1,008 SH   DFND   0 0 1,008
SHELL PLC SPON ADS 780259305   73,762 1,121 SH   DFND   0 0 1,121
SNAP INC CL A 83304A106   26,885 1,588 SH   DFND   0 0 1,588
SNOWFLAKE INC CL A 833445109   9,439,963 47,437 SH   DFND   688 0 46,749
SOCIEDAD QUIMICA MINERA DE C SPON ADR SER B 833635105   23,871,338 410,900 SH   DFND   0 0 410,900
SOCIEDAD QUIMICA MINERA DE C SPON ADR SER B 833635105   44,853,947 772,076 SH   DFND 1 83,327 0 688,749
SONY CORP SPONSORED ADR 835699307   232,369 2,454 SH   DFND   0 0 2,454
SOUTHWEST AIRLS CO COM 844741108   1,704,040 58,000 SH   DFND   0 0 58,000
SPDR GOLD TR GOLD SHS 78463V107   19,308,170 101,000 SH   DFND   0 0 101,000
SPDR INDEX SHS FDS ASIA PACIF ETF 78463X301   1,263,324 12,500 SH   DFND   0 0 12,500
SPDR S&P 500 ETF TR TR UNIT 78462F103   249,548,682 525,023 SH   DFND 1 525,023 0 0
SPDR SER TR S&P OILGAS EXP 78468R556   1,750,264 12,835 SH   DFND   0 0 12,835
SPDR SERIES TRUST S&P METALS MNG 78464A755   230,060 3,885 SH   DFND   0 0 3,885
SPDR SERIES TRUST S&P BK ETF 78464A797   264,799 5,754 SH   DFND   0 0 5,754
SPDR SERIES TRUST S&P RETAIL ETF 78464A714   4,990,051 69,229 SH   DFND   0 0 69,229
SPLUNK INC COM 848637104   456,180 3,000 SH   DFND   0 0 3,000
SQUARE INC CL A 852234103   18,487 239 SH   DFND   0 0 239
SQUARESPACE INC CLASS A 85225A107   27,431 831 SH   DFND   0 0 831
STARBUCKS CORP COM 855244109   16,226 169 SH   DFND   0 0 169
STEEL DYNAMICS INC COM 858119100   25,864 219 SH   DFND   0 0 219
STERICYCLE INC COM 858912108   5,253 106 SH   DFND   0 0 106
SUNRUN INC COM 86771W105   7,616 388 SH   DFND   0 0 388
SUZANO S A SPON COM 86959K105   1,304,877 115,629 SH   DFND   0 0 115,629
SUZANO S A SPON COM 86959K105   18,328,152 1,624,112 SH   DFND 1 361,406 0 1,262,706
T MOBILE US INC COM 872590104   33,830 211 SH   DFND   0 0 211
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100   47,071,544 452,611 SH   DFND   0 0 452,611
TAIWAN SEMICONDUCTOR MFG LTD SPONSORED ADR 874039100   1,164,800 11,200 SH   DFND 1 11,200 0 0
TAKE-TWO INTERACTIVE SOFTWAR COM 874054109   10,623 66 SH   DFND   0 0 66
TARGET CORP COM 87612E106   12,818 90 SH   DFND   0 0 90
TECHNIPFMC PLC COM G87110105   69,846 3,468 SH   DFND   0 0 3,468
TECK RESOURCES LTD CL B 878742204   4,618,985 108,376 SH   DFND   0 0 108,376
TELADOC HEALTH INC COM 87918A105   13,339 619 SH   DFND   0 0 619
TELEFONICA BRASIL SA SPONSORED ADR 87936R205   981,887 92,500 SH   DFND   0 0 92,500
TELEFONICA BRASIL SA SPONSORED ADR 87936R205   2,596,428 244,600 SH   DFND 1 32,800 0 211,800
TETRA TECH INC NEW COM 88162G103   5,843 35 SH   DFND   0 0 35
TG THERAPEUTICS INC COM 88322Q108   3,245 190 SH   DFND   0 0 190
THE TRADE DESK INC COM CL A 88339J105   16,263 226 SH   DFND   0 0 226
THERMO FISHER SCIENTIFIC INC COM 883556102   3,105,448 5,828 SH   DFND   0 0 5,828
TIM S A COM 88706T108   383,298 20,812 SH   DFND   0 0 20,812
TIM S A COM 88706T108   8,182,304 444,276 SH   DFND 1 108,331 0 335,945
TOPBUILD CORP COM 89055F103   7,111 19 SH   DFND   0 0 19
TREX CO INC COM 89531P105   5,878 71 SH   DFND   0 0 71
TRIP COM GROUP LTD ADS 89677Q107   226,863 6,300 SH   DFND   0 0 6,300
TRIP COM GROUP LTD ADS 89677Q107   226,863 6,300 SH   DFND 1 6,300 0 0
TUSIMPLE HLDGS INC CL A 90089L108   6,376 7,264 SH   DFND   0 0 7,264
UDR INC COM 902653104   821,924 21,200 SH   DFND   0 0 21,200
ULTRAGENYX PHARMACEUTICAL IN COM 90400D108   12,959 271 SH   DFND   0 0 271
UNION PAC CORP COM 907818108   6,231,987 25,333 SH   DFND   0 0 25,333
UNITED CONTL HLDGS INC COM 910047109   3,399,570 81,000 SH   DFND   0 0 81,000
UNITED STATES OIL FUND LP UNITS 91232N108   6,098,475 91,500 SH   DFND   0 0 91,500
UNITEDHEALTH GROUP INC COM 91324P102   99,503 189 SH   DFND   0 0 189
UNITY SOFTWARE INC COM 91332U101   30,504 746 SH   DFND   0 0 746
UNIVERSAL DISPLAY CORP COM 91347P105   33,662 176 SH   DFND   0 0 176
UPSTART HLDGS INC COM 91680M107   28,112 688 SH   DFND   0 0 688
VALE S A SPONSORED ADS 91912E105   72,596,298 4,560,069 SH   DFND   0 0 4,560,069
VALE S A SPONSORED ADS 91912E105   102,354,154 6,429,281 SH   DFND 1 929,105 0 5,500,176
VANECK VECTORS ETF TR SEMICONDUCTOR ET 92189F676   16,077,898 91,942 SH   DFND   0 0 91,942
VANECK VECTORS ETF TR JR GOLD MINERS E 92189F791   1,516,400 40,000 SH   DFND   40,000 0 0
VANGUARD INDEX FDS S&P 500 ETF SHS 922908363   121,004,520 277,025 SH   DFND   0 0 277,025
VANGUARD INTL EQUITY INDEX F FTSE EUROPE ETF 922042874   363,925 5,644 SH   DFND   0 0 5,644
VANGUARD INTL EQUITY INDEX F FTSE EUROPE ETF 922042874   49,471,184 767,233 SH   DFND 1 767,233 0 0
VERACYTE INC COM 92337F107   4,154 151 SH   DFND   0 0 151
VERIZON COMMUNICATIONS INC COM 92343V104   22,695 602 SH   DFND   0 0 602
VERTEX PHARMACEUTICALS INC COM 92532F100   135,494 333 SH   DFND   0 0 333
VERVE THERAPEUTICS INC COM 92539P101   26,179 1,878 SH   DFND   0 0 1,878
VESTA REAL ESTATE CORPORATIO ADS 92540K109   1,600,157 40,408 SH   DFND   0 0 40,408
VIMEO INC COMMON STOCK 92719V100   19,420 4,954 SH   DFND   0 0 4,954
VIRGIN GALACTIC HOLDINGS INC COM 92766K106   28,449 11,612 SH   DFND   0 0 11,612
VISA INC COM CL A 92826C839   3,972,345 15,258 SH   DFND   0 0 15,258
VORNADO RLTY TR SH BEN INT 929042109   8,729 309 SH   DFND   0 0 309
VUZIX CORP COM NEW 92921W300   8,667 4,157 SH   DFND   0 0 4,157
WABTEC CORP COM 929740108   14,086 111 SH   DFND   0 0 111
WALMART INC COM 931142103   67,001 425 SH   DFND   0 0 425
WASTE MGMT INC DEL COM 94106L109   77,013 430 SH   DFND   0 0 430
WATERS CORP COM 941848103   71,443 217 SH   DFND   0 0 217
WESTLAKE CHEM CORP COM 960413102   84,396 603 SH   DFND   0 0 603
WEYERHAEUSER CO COM 962166104   44,610 1,283 SH   DFND   0 0 1,283
WISDOMTREE TR INDIA ERNGS FD 97717W422   902,000 22,000 SH   DFND   0 0 22,000
WOLFSPEED INC COM 977852102   18,274 420 SH   DFND   0 0 420
WORTHINGTON INDS INC COM 981811102   85,059 1,478 SH   DFND   0 0 1,478
XP INC CL A G98239109   11,061,238 421,886 SH   DFND   0 0 421,886
XP INC CL A G98239109   708,858 29,700 SH   DFND 1 0 0 29,700
XPERI HOLDING CORP COMMON STOCK 98423J101   12,640 1,147 SH   DFND   0 0 1,147
XYLEM INC COM 98419M100   13,037 114 SH   DFND   0 0 114
YPF SOCIEDAD ANONIMA SPON ADR CL D 984245100   2,007,180 118,000 SH   DFND   0 0 118,000
YUM BRANDS INC COM 988498101   18,554 142 SH   DFND   0 0 142
ZIM INTEGRATED SHIPPING SERV SHS M9T951109   141,141 14,300 SH   DFND   0 0 14,300
ZIM INTEGRATED SHIPPING SERV SHS M9T951109   141,141 14,300 SH   DFND 1 14,300 0 0
ZOOM VIDEO COMMUNICATIONS IN CL A 98980L101   447,784 6,227 SH   DFND   5,286 0 941