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Cash and Cash Equivalents, and Marketable Securities (ASU 2016-01 and Biocartis) (Details)
€ in Millions
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Dec. 31, 2017
EUR (€)
shares
Dec. 31, 2017
USD ($)
Jun. 30, 2018
USD ($)
Jun. 30, 2018
USD ($)
Dec. 31, 2017
USD ($)
Jan. 01, 2018
USD ($)
Dec. 31, 2017
USD ($)
shares
Marketable securities              
Accumulated deficit     $ (227,460,000) $ (227,460,000)     $ (245,945,000)
Unrealized gain on revaluation of equity investment     1,283,000 1,410,000      
Biocartis N.V.              
Marketable securities              
Amount invested in shares of common stock € 3.4 $ 4,000,000          
Estimated fair value, equity securities € 3.0           $ 3,500,000
Unrealized losses recorded in other comprehensive income         $ 180,000    
Unrealized gain on revaluation of equity investment     90,000 218,000      
Foreign currency revaluation gain (loss)     $ (231,000) $ (91,000)      
Biocartis N.V. | Common Stock              
Marketable securities              
Number of shares purchased | shares 270,000           270,000
ASU 2016-01              
Marketable securities              
Accumulated deficit           $ 180,000