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Collaboration and Commercial Technology Licensing Agreements (Biocartis) (Details)
$ / shares in Units, $ in Thousands, € in Millions
1 Months Ended 3 Months Ended 12 Months Ended
Dec. 31, 2017
EUR (€)
Dec. 31, 2017
USD ($)
$ / shares
shares
Mar. 31, 2018
USD ($)
Mar. 31, 2017
USD ($)
Dec. 31, 2017
EUR (€)
Dec. 31, 2017
USD ($)
$ / shares
shares
Sep. 30, 2017
EUR (€)
Collaboration agreements              
Amount invested     $ 24,043 $ 20,599      
Exclusive license and development agreement with Biocartis NV              
Collaboration agreements              
Number of shares purchased | shares   270,000       270,000  
Market price | $ / shares   $ 12.50       $ 12.50  
Amount invested € 3.4 $ 4,000          
Estimated fair value   $ 3,500 $ 3,800     $ 3,500  
Cash obligation upon achievement of certain milestones | €             € 6.5
Exclusive license and development agreement with Biocartis NV | Research and development              
Collaboration agreements              
Upfront license and option fee payment         € 2.8 $ 3,200