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Organization and Summary of Significant Accounting Policies (Marketable Securities Sold) (Details) - USD ($)
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Investments in Privately Held Companies        
Proceeds from sales of marketable securities     $ 10,155,000 $ 5,117,000
Realized gains on available-for-sale marketable securities     2,807,000 2,009,000
Amount reclassified out of accumulated other comprehensive income     1,127,000 787,000
Invitae        
Investments in Privately Held Companies        
Carrying value   $ 10,700,000   10,700,000
Amount reclassified out of accumulated other comprehensive income     1,100,000 787,000
Amount reclassified out of accumulated other comprehensive income, tax portion     821,000 448,000
Common Stock | Sale | Invitae        
Investments in Privately Held Companies        
Proceeds from sales of marketable securities     $ 10,200,000 $ 5,100,000
Cost per share (in dollars per share)     $ 6.28 $ 6.28
Realized gains on available-for-sale marketable securities     $ 2,800,000 $ 2,000,000
Number of shares of cost method investment sold by entity 0 0