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Organization and Summary of Significant Accounting Policies (Marketable Securities Sold) (Details) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2017
Jun. 30, 2016
Investments in Privately Held Companies      
Proceeds from sales of marketable securities   $ 10,155,000 $ 5,117,000
Realized gains on available-for-sale marketable securities $ 676,000 2,807,000 2,009,000
Amount reclassified out of accumulated other comprehensive income 345,000 1,127,000 787,000
Invitae      
Investments in Privately Held Companies      
Carrying value $ 10,700,000   10,700,000
Amount reclassified out of accumulated other comprehensive income   1,100,000 787,000
Amount reclassified out of accumulated other comprehensive income, tax portion   821,000 448,000
Common Stock | Sale | Invitae      
Investments in Privately Held Companies      
Proceeds from sales of marketable securities   $ 10,200,000 $ 5,100,000
Cost per share (in dollars per share)   $ 6.28 $ 6.28
Realized gains on available-for-sale marketable securities   $ 2,800,000 $ 2,000,000