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Organization and Summary of Significant Accounting Policies (Marketable Securities Sold) (Details) - USD ($)
1 Months Ended 12 Months Ended
Jan. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Investments in Privately Held Companies        
Proceeds from sales of marketable securities   $ 9,717,000    
Realized gains on available-for-sale marketable securities   3,208,000 $ 0 $ 0
Amount reclassified out of accumulated other comprehensive income   1,854,000    
Invitae        
Investments in Privately Held Companies        
Fair value   9,300,000 18,100,000  
Carrying value   7,300,000   13,900,000
Amount reclassified out of accumulated other comprehensive income   1,900,000 $ 0 $ 0
Amount reclassified out of accumulated other comprehensive income, tax portion   727,000    
Common Stock | Sale | Invitae        
Investments in Privately Held Companies        
Proceeds from sales of marketable securities $ 10,200,000 $ 9,700,000    
Cost per share (in dollars per share)   $ 6.28    
Realized gains on available-for-sale marketable securities $ 2,800,000 $ 3,200,000    
Number of shares of cost method investment sold by entity     0