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Collaboration and Commercial Technology Licensing Agreements (Details)
1 Months Ended 3 Months Ended 6 Months Ended
Jun. 30, 2016
USD ($)
item
Jun. 30, 2016
USD ($)
Jun. 30, 2015
USD ($)
Mar. 31, 2015
USD ($)
Dec. 31, 2013
USD ($)
Jun. 30, 2016
USD ($)
Sep. 30, 2015
USD ($)
Jun. 30, 2015
USD ($)
Specimen transfer agreements                
Collaboration payments and costs                
Collaboration expense   $ 1,600,000 $ 2,300,000     $ 2,500,000   $ 9,400,000
Technology license agreements                
Collaboration payments and costs                
Costs recorded under collaborative arrangements   2,500,000 $ 2,300,000     5,100,000 $ 4,500,000  
Exclusive license agreement                
Collaboration payments and costs                
Collaboration expense               $ 5,500,000
Estimated total remaining obligation, including milestone payments           $ 0    
Exclusive license agreement | Research and development expense.                
Collaboration payments and costs                
Up-front payment         $ 9,000,000      
Milestone payment       $ 5,500,000        
Oncotype DX DCIS clinical study                
Collaboration payments and costs                
Period from achieving key milestone entity required to make fixed annual payments           1 year    
Fixed annual payments                
2016 $ 604,000 604,000       $ 604,000    
2017 504,000 504,000       504,000    
Exclusive distribution rights Epic's AR-V7 liquid biopsy test in United States                
Collaboration payments and costs                
Obligation upon achievement of certain milestones 4,000,000 4,000,000       4,000,000    
Investment in subordinated convertible promissory notes per agreement $ 7,500,000 7,500,000       7,500,000    
Number of milestones needed to be achieved for conversion into preferred stock | item 1              
Investment in preferred stock per collaboration agreement $ 2,500,000 $ 2,500,000       $ 2,500,000    
Term of agreement 10 years