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Organization and Summary of Significant Accounting Policies Concentration of Risk (Details) - product
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Concentration of Risk      
Number of products from which the majority of the entity's product revenues have been derived 1    
Product revenues | Third-party payor      
Concentration of Risk      
Number of products from which the majority of the entity's product revenues have been derived 1    
Product revenues | Third-party payor | Medicare      
Concentration of Risk      
Concentration risk percentage 20.00% 20.00% 21.00%
Net accounts receivable | Third-party payor | Medicare      
Concentration of Risk      
Concentration risk percentage 14.00% 27.00%