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Condensed Consolidated Statements of Cash Flows (USD $)
In Thousands, unless otherwise specified
3 Months Ended
Mar. 31, 2015
Mar. 31, 2014
Operating activities    
Net loss $ (9,493)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic $ (7,445)us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:    
Depreciation and amortization 1,728us-gaap_DepreciationDepletionAndAmortization 1,757us-gaap_DepreciationDepletionAndAmortization
Employee stock-based compensation 4,176us-gaap_ShareBasedCompensation 4,356us-gaap_ShareBasedCompensation
Write-off of previously capitalized software costs 87ghdx_WriteOffOfPreviouslyCapitalizedCosts  
Impairment of assets held for sale   265us-gaap_AssetImpairmentCharges
Outside director restricted stock awarded in lieu of fees 50us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims 50us-gaap_IssuanceOfStockAndWarrantsForServicesOrClaims
(Gain) loss on disposal of property and equipment (19)us-gaap_GainLossOnSaleOfPropertyPlantEquipment 33us-gaap_GainLossOnSaleOfPropertyPlantEquipment
Changes in assets and liabilities:    
Accounts receivable (63)us-gaap_IncreaseDecreaseInAccountsReceivable 545us-gaap_IncreaseDecreaseInAccountsReceivable
Prepaid expenses and other assets (7,878)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets (315)us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets
Accounts payable 239us-gaap_IncreaseDecreaseInAccountsPayable 2,367us-gaap_IncreaseDecreaseInAccountsPayable
Accrued compensation and employee benefits (1,320)us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities (1,377)us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities
Accrued expenses and other liabilities 5,283us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities 468us-gaap_IncreaseDecreaseInAccruedLiabilitiesAndOtherOperatingLiabilities
Deferred revenues (67)us-gaap_IncreaseDecreaseInDeferredRevenue (578)us-gaap_IncreaseDecreaseInDeferredRevenue
Net cash (used in) provided by operating activities (7,277)us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations 126us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperations
Investing activities    
Purchases of property and equipment (4,369)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment (1,169)us-gaap_PaymentsToAcquirePropertyPlantAndEquipment
Purchases of marketable securities (31,274)us-gaap_PaymentsToAcquireAvailableForSaleSecurities (23,326)us-gaap_PaymentsToAcquireAvailableForSaleSecurities
Maturities of marketable securities 37,180us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities 21,500us-gaap_ProceedsFromSaleAndMaturityOfAvailableForSaleSecurities
Net cash provided by (used in) investing activities 1,537us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations (2,995)us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperations
Financing activities    
Net proceeds from issuance of common stock under stock plans 2,379us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions 996us-gaap_ProceedsFromIssuanceOfSharesUnderIncentiveAndShareBasedCompensationPlansIncludingStockOptions
Withholding taxes related to restricted stock units net share settlement (3,427)us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation (3,165)us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation
Net cash used in financing activities (1,048)us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations (2,169)us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperations
Net decrease in cash and cash equivalents (6,788)us-gaap_NetCashProvidedByUsedInContinuingOperations (5,038)us-gaap_NetCashProvidedByUsedInContinuingOperations
Cash and cash equivalents at the beginning of the period 29,726us-gaap_CashAndCashEquivalentsAtCarryingValue 33,279us-gaap_CashAndCashEquivalentsAtCarryingValue
Cash and cash equivalents at the end of the period 22,938us-gaap_CashAndCashEquivalentsAtCarryingValue 28,241us-gaap_CashAndCashEquivalentsAtCarryingValue
Non-cash investing and financing activities    
Accrued purchase of property and equipment 2,501us-gaap_CapitalExpendituresIncurredButNotYetPaid 1,750us-gaap_CapitalExpendituresIncurredButNotYetPaid
Change in fair value of corporate equity securities $ 23,145ghdx_NonCashAvailableForSaleEquitySecuritiesAccumulatedGrossUnrealizedGainBeforeTax