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Commitments (Details) (USD $)
1 Months Ended 1 Months Ended 1 Months Ended
Jun. 30, 2014
Nov. 30, 2010
Leased laboratory and office space located in Redwood City, California
Sep. 30, 2005
Leased laboratory and office space located in Redwood City, California
sqft
Nov. 30, 2010
Leased laboratory and office space located near the leased facility in Redwood City, California
Jan. 31, 2007
Leased laboratory and office space located near the leased facility in Redwood City, California
sqft
Oct. 31, 2009
Leased office space located near the leased facility in Redwood City, California
sqft
Aug. 31, 2013
Second leased laboratory and office space located near the leased facility in Redwood City, California
sqft
Jul. 31, 2014
Second leased laboratory and office space located near the leased facility in Redwood City, California
Subsequent event
sqft
May 31, 2014
Leased office space located in Geneva, Switzerland
European subsidiary
sqft
May 31, 2010
Leased office space located in Geneva, Switzerland
European subsidiary
sqft
Non-cancelable operating leases                    
Area leased under non-cancelable operating lease agreement (in square feet)     48,000   48,000 30,500 18,400     2,500
Period of time for which entity has an option to extend lease term   5 years   5 years   5 years 5 years      
Additional area leased (in square feet)               5,500 5,000  
Lease incentive obligations     $ 834,000   $ 283,000 $ 307,000 $ 276,000      
Non-cancelable commitments under operating leases                    
2014 (remainder of year) 1,856,000                  
2015 3,799,000                  
2016 3,726,000                  
2017 3,706,000                  
2018 2,310,000                  
2019 and thereafter 461,000                  
Total minimum payments $ 15,858,000