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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
 RnQmVVeMVBHVDel8RbM9tPCeweMfK2C0PWClzpayGNVZntDKRuTddcoY0NRVBTr8
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<SEC-DOCUMENT>0000903423-05-000794.txt : 20051006
<SEC-HEADER>0000903423-05-000794.hdr.sgml : 20051006
<ACCEPTANCE-DATETIME>20051006172405
ACCESSION NUMBER:		0000903423-05-000794
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20051004
FILED AS OF DATE:		20051006
DATE AS OF CHANGE:		20051006

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			GENOMIC HEALTH INC
		CENTRAL INDEX KEY:			0001131324
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		IRS NUMBER:				770552594

	BUSINESS ADDRESS:	
		STREET 1:		301 PENOBSCOT DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063
		BUSINESS PHONE:		650-556-9300

	MAIL ADDRESS:	
		STREET 1:		301 PENOBSCOT DRIVE
		CITY:			REDWOOD CITY
		STATE:			CA
		ZIP:			94063

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Cohen Fred E
		CENTRAL INDEX KEY:			0001339358

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-51541
		FILM NUMBER:		051127844

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		1 415 743 1661

	MAIL ADDRESS:	
		STREET 1:		345 CALIFORNIA STREET SUITE 2600
		CITY:			SAN FRANCISCO
		STATE:			CA
		ZIP:			94104
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>cohen-f4_1005ex.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-10-04</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001131324</issuerCik>
        <issuerName>GENOMIC HEALTH INC</issuerName>
        <issuerTradingSymbol>GHDX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001339358</rptOwnerCik>
            <rptOwnerName>Cohen Fred E</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O TPG VENTURES</rptOwnerStreet1>
            <rptOwnerStreet2>345 CALIFORNIA STREET SUITE 2600</rptOwnerStreet2>
            <rptOwnerCity>SAN FRANCISCO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94104</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock par value $1.00</value>
            </securityTitle>
            <transactionDate>
                <value>2005-10-04</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>33333</value>
                    <footnoteId id="F2"/>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>43351</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Series A Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-10-04</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>C</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>99999</value>
                    <footnoteId id="F5"/>
                </transactionShares>
                <transactionPricePerShare>
                    <footnoteId id="F2"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F3"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F4"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>33333</value>
                    <footnoteId id="F2"/>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">On September 8, 2005, the Issuer declared a conditional dividend of 791,210 shares of Common Stock to be distributed on a pro
rata basis to the Issuer's stockholders of record at the commencement of the Issuer's initial public offering (&quot;IPO&quot;) if the
price per share of Common Stock sold in the IPO is $11.40 or greater. As a result, the Reporting Person received 1,685
shares of Common Stock as of October 4, 2005, the closing date of the IPO, which is reflected in the amount of Common Stock
reported in column 5.</footnote>
        <footnote id="F2">Every three shares of Preferred Stock were converted into one share of Common Stock upon consummation of the IPO. This
conversion rate is reflected in the amount of securities underlying the derivative security reported in column 7, which also
reflects adjustment for the stock split by the Issuer on September 8, 2005.</footnote>
        <footnote id="F3">These securities are exercisable immediately.</footnote>
        <footnote id="F4">These securities to do not have an expiration date.</footnote>
        <footnote id="F5">Does not include 1,014,492 shares of Series D Preferred Stock and 821,513 shares of Series E Preferred Stock previously held
by funds managed by Tarrant Advisors, Inc., with which Mr. Cohen is affiliated. These shares of Preferred Stock were also
converted on
October 4, 2005 as reported in a seperate Form 4 filed by Tarrant Advisors, Inc.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Fred E. Cohen</signatureName>
        <signatureDate>2005-10-04</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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