X0303 4 2009-10-15 0 0001131096 ATHENAHEALTH INC ATHN 0001412213 Bush Jonathan C/O ATHENAHEALTH, INC. 311 ARSENAL STREET WATERTOWN MA 02472 1 1 0 0 CEO and President Common Stock 2009-10-15 4 S 0 190 38.96 D 241974 I See Footnote Common Stock 2009-10-15 4 S 0 100 38.81 D 241874 I See Footnote Common Stock 2009-10-15 4 S 0 100 38.83 D 241774 I See Footnote Common Stock 2009-10-15 4 S 0 200 38.73 D 241574 I See Footnote Common Stock 2009-10-15 4 S 0 100 38.95 D 241474 I See Footnote Common Stock 332832 D Common Stock 100000 I See Footnote Common Stock 2354 I See Footnote The sales reported on this Form 4 were made pursuant to a written trading plan adopted by the trustees of The Bush 2004 Gift Trust (see footnote 2) on June 9, 2009, in accordance with Rule 10b5-1. These shares are owned by The Bush 2004 Gift Trust, the beneficiaries of which are certain of Mr. Bush's children. The Reporting Person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose. These shares are owned by The Jonathan J. Bush, Jr. Grantor Retained Annuity Trust Dated July 15, 2008, the beneficiaries of which are Mr. Bush and certain of his children. The Reporting Person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose. These shares are owned by The Oscar W. Bush 2007 Gift Trust, the beneficiary of which is Mr. Bush's child. The Reporting Person disclaims beneficial ownership of these securities, and this report shall not be deemed an admission that the Reporting Person is the beneficial owner of the securities for purposes of Section 16 or for any other purpose. /s/ Daniel H. Orenstein Attorney-in-Fact 2009-10-15