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<submissionType>SCHEDULE 13G</submissionType>
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<filer>
<filerCredentials>
<cik>1224962</cik>
<ccc>XXXXXXXX</ccc>
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<securitiesClassTitle>Common Stock, par value $0.01 per share</securitiesClassTitle>
<eventDateRequiresFilingThisStatement>12/31/2024</eventDateRequiresFilingThisStatement>
<issuerInfo>
<issuerCik>0001130598</issuerCik>
<issuerName>Traws Pharma, Inc.</issuerName>
<issuerCusip>68232V884</issuerCusip>
<issuerPrincipalExecutiveOfficeAddress>
<street1 xmlns="http://www.sec.gov/edgar/common">12 PENNS TRAIL</street1>
<city xmlns="http://www.sec.gov/edgar/common">NEWTOWN</city>
<stateOrCountry xmlns="http://www.sec.gov/edgar/common">PA</stateOrCountry>
<zipCode xmlns="http://www.sec.gov/edgar/common">18940</zipCode>
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<designateRulesPursuantThisScheduleFiled>
<designateRulePursuantThisScheduleFiled>Rule 13d-1(c)</designateRulePursuantThisScheduleFiled>
</designateRulesPursuantThisScheduleFiled>
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<reportingPersonName>Perceptive Advisors LLC</reportingPersonName>
<citizenshipOrOrganization>DE</citizenshipOrOrganization>
<reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>386555</sharedVotingPower>
<soleDispositivePower>0</soleDispositivePower>
<sharedDispositivePower>386555</sharedDispositivePower>
</reportingPersonBeneficiallyOwnedNumberOfShares>
<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>386555</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
<aggregateAmountExcludesCertainSharesFlag>N</aggregateAmountExcludesCertainSharesFlag>
<classPercent>9.9</classPercent>
<typeOfReportingPerson>IA</typeOfReportingPerson>
</coverPageHeaderReportingPersonDetails>
<coverPageHeaderReportingPersonDetails>
<reportingPersonName>Joseph Edelman</reportingPersonName>
<citizenshipOrOrganization>X1</citizenshipOrOrganization>
<reportingPersonBeneficiallyOwnedNumberOfShares>
<soleVotingPower>0</soleVotingPower>
<sharedVotingPower>386555</sharedVotingPower>
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<typeOfReportingPerson>IN</typeOfReportingPerson>
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<coverPageHeaderReportingPersonDetails>
<reportingPersonName>Perceptive Life Sciences Master Fund, Ltd</reportingPersonName>
<citizenshipOrOrganization>E9</citizenshipOrOrganization>
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<reportingPersonBeneficiallyOwnedAggregateNumberOfShares>386555</reportingPersonBeneficiallyOwnedAggregateNumberOfShares>
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<classPercent>9.9</classPercent>
<typeOfReportingPerson>CO</typeOfReportingPerson>
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<item1>
<issuerName>Traws Pharma, Inc.</issuerName>
<issuerPrincipalExecutiveOfficeAddress>12 Penns Trail Newtown, PA 18940</issuerPrincipalExecutiveOfficeAddress>
</item1>
<item2>
<filingPersonName>Perceptive Advisors LLC (Perceptive Advisors)
Joseph Edelman (Mr. Edelman)
Perceptive Life Sciences Master Fund, Ltd. (the Master Fund)
</filingPersonName>
<principalBusinessOfficeOrResidenceAddress>51 Astor Place, 10th Floor
New York, NY 10003
</principalBusinessOfficeOrResidenceAddress>
<citizenship>Perceptive Advisors is a Delaware limited liability company. Mr. Edelman is a United States citizen. The Master Fund is a Cayman Islands corporation </citizenship>
</item2>
<item3>
<notApplicableFlag>Y</notApplicableFlag>
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<amountBeneficiallyOwned>386,555</amountBeneficiallyOwned>
<classPercent>9.9</classPercent>
<numberOfSharesPersonHas>
<solePowerOrDirectToVote>0</solePowerOrDirectToVote>
<sharedPowerOrDirectToVote>386,555</sharedPowerOrDirectToVote>
<solePowerOrDirectToDispose>0</solePowerOrDirectToDispose>
<sharedPowerOrDirectToDispose>386,555</sharedPowerOrDirectToDispose>
</numberOfSharesPersonHas>
</item4>
<item5>
<notApplicableFlag>Y</notApplicableFlag>
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<item6>
<notApplicableFlag>Y</notApplicableFlag>
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<item7>
<notApplicableFlag>Y</notApplicableFlag>
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<item8>
<notApplicableFlag>Y</notApplicableFlag>
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<item9>
<notApplicableFlag>Y</notApplicableFlag>
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<item10>
<notApplicableFlag>N</notApplicableFlag>
<certifications>By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under &amp;#167; 240.14a-11.</certifications>
</item10>
</items>
<signatureInformation>
<reportingPersonName>Perceptive Advisors LLC</reportingPersonName>
<signatureDetails>
<signature>/s/ Joseph Edelman</signature>
<title>Managing Member</title>
<date>01/08/2025</date>
</signatureDetails>
</signatureInformation>
<signatureInformation>
<reportingPersonName>Joseph Edelman</reportingPersonName>
<signatureDetails>
<signature>/s/ Joseph Edelman</signature>
<title>Managing Member</title>
<date>01/08/2025</date>
</signatureDetails>
</signatureInformation>
<signatureInformation>
<reportingPersonName>Perceptive Life Sciences Master Fund, Ltd</reportingPersonName>
<signatureDetails>
<signature>Perceptive Advisors LLC</signature>
<title>Joseph Edelman Managing Member</title>
<date>01/08/2025</date>
</signatureDetails>
<signatureDetails>
<signature>/s/ Joseph Edelman</signature>
<title>Managing Member</title>
<date>01/08/2025</date>
</signatureDetails>
</signatureInformation>
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