X0306 4 2013-01-14 0 0001130591 XENOPORT INC XNPT 0001414719 Angotti Vincent C/O XENOPORT, INC. 3410 CENTRAL EXPRESSWAY SANTA CLARA CA 95051 0 1 0 0 Executive VP, COO Common Stock 2013-01-14 4 M 0 1250 0.00 A 32860 D Common Stock 2013-01-14 4 F 0 548 8.80 D 32312 D Common Stock 2013-01-14 4 M 0 6250 0.00 A 38562 D Common Stock 2013-01-14 4 F 0 2438 8.80 D 36124 D Common Stock 2013-01-14 4 M 0 7500 0.00 A 43624 D Common Stock 2013-01-14 4 F 0 3291 8.80 D 40333 D Restricted Stock Unit 2013-01-14 4 M 0 1250 0.00 A Common Stock 1250 1250 D Restricted Stock Unit 2013-01-14 4 M 0 6250 0.00 A Common Stock 6250 12500 D Restricted Stock Unit 2013-01-14 4 M 0 7500 0.00 A Common Stock 7500 22500 D Restricted Stock Unit 2013-01-14 4 A 0 30000 0.00 A Common Stock 30000 30000 D Employee Stock Option 8.80 2013-01-14 4 A 0 75000 0.00 A 2023-01-14 Common Stock 75000 75000 D Includes 2,543 shares acquired through the Issuer's Employee Stock Purchase Plan on November 15, 2012. Each restricted stock unit represents a contingent right to receive one share of XenoPort, Inc. common stock. The restricted stock units shall vest over four years from the grant date, January 13, 2010, in equal annual installments. The restricted stock units shall vest over four years from the grant date, January 13, 2011, in equal annual installments. The restricted stock units shall vest over three years from the grant date, January 13, 2012, with 25% vesting on the first anniversary date, 25% vesting on the second anniversary date and 50% vesting on the third anniversary date from the date of grant. The restricted stock units shall vest over four years from the grant date, January 14, 2013, in equal annual installments. The shares shall vest and become exercisable in a series of forty-eight successive equal monthly installments over the four-year period measured from the grant date, January 14, 2013. /s/ Stephanie L. Arata Attorney-in-fact 2013-01-16