X0202 4 2008-04-01 0 0001130591 XENOPORT INC XNPT 0001322961 Harris William G C/O XENOPORT, INC. 3410 CENTRAL EXPRESSWAY SANTA CLARA CA 95051 0 1 0 0 SVP, Finance and CFO Common stock 2008-04-01 4 S 0 100 41.41 D 38610 D Common stock 2008-04-01 4 S 0 100 42.00 D 38510 D Common stock 2008-04-01 4 S 0 99 41.93 D 38411 D Common stock 2008-04-01 4 S 0 1 41.92 D 38410 D Common stock 2008-04-01 4 S 0 100 42.27 D 38310 D Common stock 2008-04-01 4 S 0 100 42.34 D 38210 D Common stock 2008-04-01 4 S 0 100 42.45 D 38110 D Common stock 2008-04-01 4 S 0 100 42.46 D 38010 D Common stock 2008-04-01 4 S 0 100 41.86 D 37910 D Common stock 2008-04-01 4 S 0 100 41.48 D 37810 D Common stock 2008-04-01 4 S 0 100 42.39 D 37710 D The sales were effected pursuant to instructions given by the reporting person pursuant to a 10b5-1 trading plan. /s/ Martyn J. Webster Attorney-in-fact 2008-04-02