The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
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COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
10X GENOMICS INC CLASS A COMMON STOCK 88025U109   122,730 3,368 SH   SOLE   122,730 0 0
360 DIGITECH INC ADR USD.00001 88557W101   66,883 3,285 SH   SOLE   66,883 0 0
3M CO W/D COMMON STOCK USD.01 88579Y101   225,330 1,879 SH   SOLE   225,330 0 0
7 ACQUISITION CORP A COMMON STOCK USD.0001 G80694105   515,000 50,000 SH   SOLE   515,000 0 0
7 ACQUISITION CORP A 7 ACQUISITION CORP A CW23 G80694113   2,373 25,000 SH   SOLE   2,373 0 0
A10 NETWORKS INC COMMON STOCK USD.00001 002121101   365,444 21,975 SH   SOLE   365,444 0 0
AAR CORP COMMON STOCK USD1.0 000361105   269,490 6,002 SH   SOLE   269,490 0 0
ABBOTT LABORATORIES COMMON STOCK 002824100   3,927,188 35,770 SH   SOLE   3,927,188 0 0
ABBVIE INC COMMON STOCK USD.01 00287Y109   2,452,270 15,174 SH   SOLE   2,452,270 0 0
ABG ACQUISITION CORP I A COMMON STOCK USD.0001 G00496102   783,842 77,685 SH   SOLE   783,842 0 0
ACADEMY SPORTS OUTDOORS IN COMMON STOCK USD.01 00402L107   1,904,890 36,256 SH   SOLE   1,904,890 0 0
ACADIA PHARMACEUTICALS INC COMMON STOCK USD.0001 004225108   210,590 13,228 SH   SOLE   210,590 0 0
ACCENTURE PLC CL A COMMON STOCK USD.0000225 G1151C101   1,033,738 3,874 SH   SOLE   1,033,738 0 0
ACI WORLDWIDE INC COMMON STOCK USD.005 004498101   701,753 30,511 SH   SOLE   701,753 0 0
ACROPOLIS INFRASTRUCTURE A COMMON STOCK USD.0001 005029103   1,985,980 199,998 SH   SOLE   1,985,980 0 0
ACROPOLIS INFRASTRUCTURE A ACROPOLIS INFRASTRUCTU CW26 005029111   8,000 66,666 SH   SOLE   8,000 0 0
ACROPOLIS INFRASTRUCTURE ACQ UNIT USD.0001 005029202   20 2 SH   SOLE   20 0 0
ACTIVISION BLIZZARD INC COMMON STOCK USD.000001 00507V109   5,374,652 70,211 SH   SOLE   5,374,652 0 0
ACUITY BRANDS INC COMMON STOCK USD.01 00508Y102   1,832,475 11,065 SH   SOLE   1,832,475 0 0
ACUSHNET HOLDINGS CORP COMMON STOCK USD.001 005098108   973,183 22,920 SH   SOLE   973,183 0 0
ADAPTIVE BIOTECHNOLOGIES COMMON STOCK USD.0001 00650F109   111,926 14,650 SH   SOLE   111,926 0 0
ADIT EDTECH ACQUISITION ADIT EDTECH ACQ CW27 007024110   750 12,500 SH   SOLE   750 0 0
ADOBE INC COMMON STOCK USD.0001 00724F101   15,175,820 45,095 SH   SOLE   15,175,820 0 0
ADVANCE AUTO PARTS INC COMMON STOCK USD.0001 00751Y106   23,819 162 SH   SOLE   23,819 0 0
ADVANCED DRAINAGE SYSTEMS IN COMMON STOCK USD.01 00790R104   486,328 5,933 SH   SOLE   486,328 0 0
ADVANCED ENERGY INDUSTRIES COMMON STOCK USD.001 007973100   737,108 8,593 SH   SOLE   737,108 0 0
ADVANCED MICRO DEVICES COMMON STOCK USD.01 007903107   131,354 2,028 SH   SOLE   131,354 0 0
ADVANSIX INC COMMON STOCK USD.01 00773T101   177,363 4,665 SH   SOLE   177,363 0 0
AECOM COMMON STOCK USD.01 00766T100   823,481 9,696 SH   SOLE   823,481 0 0
AERCAP HOLDINGS NV COMMON STOCK EUR.01 N00985106   127,779 2,191 SH   SOLE   127,779 0 0
AES CORP COMMON STOCK USD.01 00130H105   44,837 1,559 SH   SOLE   44,837 0 0
AEVA TECHNOLOGIES INC INTERPRIVATE ACQUISITI CW24 00835Q111   0 2 SH   SOLE   0 0 0
AFFILIATED MANAGERS GROUP COMMON STOCK USD.01 008252108   1,161,292 7,330 SH   SOLE   1,161,292 0 0
AFLAC INC COMMON STOCK USD.1 001055102   356,535 4,956 SH   SOLE   356,535 0 0
AFRICAN GOLD ACQUISITION C A WARRANT G0112R124   2 7,500 SH   SOLE   2 0 0
AFRICAN GOLD ACQUISITION C A COMMON STOCK USD.0001 G0112R108   100,500 10,000 SH   SOLE   100,500 0 0
AFTERNEXT HEALTHTECH ACQUI A COMMON STOCK USD.0001 G01109100   1,503,000 150,000 SH   SOLE   1,503,000 0 0
AFTERNEXT HEALTHTECH ACQUI A AFTERNEXT HEALTHTECH CW23 G01109126   3,750 50,000 SH   SOLE   3,750 0 0
AGCO CORP COMMON STOCK USD.01 001084102   2,853,963 20,578 SH   SOLE   2,853,963 0 0
AGILE GROWTH CORP UNIT USD.0001 G01202129   41 4 SH   SOLE   41 0 0
AGILE GROWTH CORP A COMMON STOCK USD.0001 G01202103   1,008,960 99,996 SH   SOLE   1,008,960 0 0
AGILE GROWTH CORP A AGILE GROWTH CORP CW27 G01202111   628 33,332 SH   SOLE   628 0 0
AGILENT TECHNOLOGIES INC COMMON STOCK USD.01 00846U101   10,711,498 71,577 SH   SOLE   10,711,498 0 0
AGREE REALTY CORP REIT USD.0001 008492100   566,518 7,987 SH   SOLE   566,518 0 0
AIR LEASE CORP COMMON STOCK USD.01 00912X302   16,828 438 SH   SOLE   16,828 0 0
AIR PRODUCTS CHEMICALS INC COMMON STOCK USD1.0 009158106   204,685 664 SH   SOLE   204,685 0 0
AKAMAI TECHNOLOGIES INC COMMON STOCK USD.01 00971T101   38,947 462 SH   SOLE   38,947 0 0
ALBANY INTL CORP CL A COMMON STOCK USD.001 012348108   508,626 5,159 SH   SOLE   508,626 0 0
ALBEMARLE CORP COMMON STOCK USD.01 012653101   405,962 1,872 SH   SOLE   405,962 0 0
ALDEYRA THERAPEUTICS INC COMMON STOCK USD.001 01438T106   1,604,217 230,491 SH   SOLE   1,604,217 0 0
ALEXANDRIA REAL ESTATE EQUIT REIT USD.01 015271109   1,882,056 12,920 SH   SOLE   1,882,056 0 0
ALKERMES PLC COMMON STOCK USD.01 G01767105   357,485 13,681 SH   SOLE   357,485 0 0
ALLEGION PLC COMMON STOCK USD.01 G0176J109   1,066,705 10,134 SH   SOLE   1,066,705 0 0
ALLIANT ENERGY CORP COMMON STOCK USD.01 018802108   533,163 9,657 SH   SOLE   533,163 0 0
ALLISON TRANSMISSION HOLDING COMMON STOCK USD.01 01973R101   1,131,853 27,208 SH   SOLE   1,131,853 0 0
ALLSTATE CORP COMMON STOCK USD.01 020002101   132,210 975 SH   SOLE   132,210 0 0
ALPHA PARTNERS TECHNOLOGY A ALPHA PARTNERS TECHNOLOGY CW G63290103   1,467 33,332 SH   SOLE   1,467 0 0
ALPHA PARTNERS TECHNOLOGY A COMMON STOCK USD.0001 G63290111   1,004,960 99,996 SH   SOLE   1,004,960 0 0
ALPHA PARTNERS TECHNOLOGY ME UNIT USD.0001 G63290129   40 4 SH   SOLE   40 0 0
ALPHABET INC CL A COMMON STOCK USD.001 02079K305   2,859,181 32,406 SH   SOLE   2,859,181 0 0
ALPHABET INC CL C COMMON STOCK USD.001 02079K107   57,191,276 644,554 SH   SOLE   57,191,276 0 0
ALTC ACQUISITION CORP CL A COMMON STOCK USD.0001 02156V109   1,984,000 200,000 SH   SOLE   1,984,000 0 0
ALTIMAR ACQUISITION CORP A WARRANT G0370U116   1 6,250 SH   SOLE   1 0 0
ALTIMAR ACQUISITION CORP A COMMON STOCK USD.0001 G0370U108   251,750 25,000 SH   SOLE   251,750 0 0
ALTRIA GROUP INC COMMON STOCK USD.333 02209S103   1,292,496 28,276 SH   SOLE   1,292,496 0 0
ALVOTECH SA ALVOTECH SA 27 L01800116   19,875 18,750 SH   SOLE   19,875 0 0
AMALGAMATED FINANCIAL CORP COMMON STOCK USD.01 022671101   156,488 6,792 SH   SOLE   156,488 0 0
AMAZON.COM INC COMMON STOCK USD.01 023135106   50,630,748 602,747 SH   SOLE   50,630,748 0 0
AMCOR PLC COMMON STOCK USD.01 G0250X107   33,610 2,822 SH   SOLE   33,610 0 0
AMEREN CORPORATION COMMON STOCK USD.01 023608102   2,780,973 31,275 SH   SOLE   2,780,973 0 0
AMERICAN AIRLINES GROUP INC COMMON STOCK 02376R102   848,806 66,730 SH   SOLE   848,806 0 0
AMERICAN ASSETS TRUST INC REIT USD.01 024013104   569,697 21,498 SH   SOLE   569,697 0 0
AMERICAN EAGLE OUTFITTERS COMMON STOCK USD.01 02553E106   202,546 14,509 SH   SOLE   202,546 0 0
AMERICAN ELECTRIC POWER COMMON STOCK USD6.5 025537101   159,611 1,681 SH   SOLE   159,611 0 0
AMERICAN EXPRESS CO COMMON STOCK USD.2 025816109   513,431 3,475 SH   SOLE   513,431 0 0
AMERICAN HOMES 4 RENT A REIT USD.01 02665T306   2,217,701 73,580 SH   SOLE   2,217,701 0 0
AMERICAN INTERNATIONAL GROUP COMMON STOCK USD2.5 026874784   160,060 2,531 SH   SOLE   160,060 0 0
AMERICAN SOFTWARE INC CL A COMMON STOCK USD.1 029683109   248,591 16,934 SH   SOLE   248,591 0 0
AMERICAN STATES WATER CO COMMON STOCK 029899101   305,045 3,296 SH   SOLE   305,045 0 0
AMERICAN TOWER CORP REIT USD.01 03027X100   736,214 3,475 SH   SOLE   736,214 0 0
AMERICAN VANGUARD CORP COMMON STOCK USD.1 030371108   107,356 4,945 SH   SOLE   107,356 0 0
AMERICAN WOODMARK CORP COMMON STOCK 030506109   227,492 4,656 SH   SOLE   227,492 0 0
AMERICOLD REALTY TRUST INC REIT USD.01 03064D108   1,006,675 35,559 SH   SOLE   1,006,675 0 0
AMERIPRISE FINANCIAL INC COMMON STOCK USD.01 03076C106   72,238 232 SH   SOLE   72,238 0 0
AMERIS BANCORP COMMON STOCK USD1.0 03076K108   937,332 19,884 SH   SOLE   937,332 0 0
AMERISAFE INC COMMON STOCK USD.01 03071H100   145,672 2,803 SH   SOLE   145,672 0 0
AMERISOURCEBERGEN CORP COMMON STOCK USD.01 03073E105   44,576 269 SH   SOLE   44,576 0 0
AMETEK INC COMMON STOCK USD.01 031100100   23,025,577 164,798 SH   SOLE   23,025,577 0 0
AMGEN INC COMMON STOCK USD.0001 031162100   756,141 2,879 SH   SOLE   756,141 0 0
AMKOR TECHNOLOGY INC COMMON STOCK USD.001 031652100   480,223 20,026 SH   SOLE   480,223 0 0
AMN HEALTHCARE SERVICES INC COMMON STOCK USD.01 001744101   734,752 7,146 SH   SOLE   734,752 0 0
AMPHASTAR PHARMACEUTICALS IN COMMON STOCK USD.0001 03209R103   83,500 2,980 SH   SOLE   83,500 0 0
AMPHENOL CORP CL A COMMON STOCK USD.001 032095101   13,853,521 181,948 SH   SOLE   13,853,521 0 0
AMYLYX PHARMACEUTICALS INC COMMON STOCK USD.0001 03237H101   107,229 2,902 SH   SOLE   107,229 0 0
ANALOG DEVICES INC COMMON STOCK USD.167 032654105   16,590,650 101,144 SH   SOLE   16,590,650 0 0
ANGI INC COMMON STOCK 00183L102   118,948 50,616 SH   SOLE   118,948 0 0
ANSYS INC COMMON STOCK USD.01 03662Q105   766,807 3,174 SH   SOLE   766,807 0 0
ANTERO MIDSTREAM CORP COMMON STOCK 03676B102   142,547 13,211 SH   SOLE   142,547 0 0
ANTERO RESOURCES CORP COMMON STOCK USD.01 03674X106   85,749 2,767 SH   SOLE   85,749 0 0
ANTHEMIS DIGITAL ACQUISITION COMMON STOCK USD.0001 G03959106   257,125 25,000 SH   SOLE   257,125 0 0
ANTHEMIS DIGITAL ACQUISITION ANTHEMIS DIGITAL ACQ CW23 G03959114   1,125 12,500 SH   SOLE   1,125 0 0
ANZU SPECIAL ACQUISITION A COMMON STOCK USD.0001 03737A101   3,030,000 300,000 SH   SOLE   3,030,000 0 0
ANZU SPECIAL ACQUISITION A ANZU SPECIAL ACQ CW27 03737A119   3,800 100,000 SH   SOLE   3,800 0 0
AON PLC CLASS A COMMON STOCK G0403H108   172,881 576 SH   SOLE   172,881 0 0
APA CORP COMMON STOCK USD.625 03743Q108   1,919,668 41,124 SH   SOLE   1,919,668 0 0
APELLIS PHARMACEUTICALS INC COMMON STOCK USD.0001 03753U106   784,803 15,177 SH   SOLE   784,803 0 0
APOLLO STRATEGIC GROWTH CL A COMMON STOCK USD.00025 G0412A102   400,800 40,000 SH   SOLE   400,800 0 0
APOLLO STRATEGIC GROWTH CL A APOLLO STRATEGIC CL A CW27 G0412A128   1,120 8,000 SH   SOLE   1,120 0 0
APPLE HOSPITALITY REIT INC REIT NPV 03784Y200   1,542,006 97,719 SH   SOLE   1,542,006 0 0
APPLE INC COMMON STOCK USD.00001 037833100   80,510,995 619,649 SH   SOLE   80,510,995 0 0
APPLIED MATERIALS INC COMMON STOCK USD.01 038222105   2,614,945 26,853 SH   SOLE   2,614,945 0 0
ARCH CAPITAL GROUP LTD COMMON STOCK USD.01 G0450A105   109,677 1,747 SH   SOLE   109,677 0 0
ARCHER DANIELS MIDLAND CO COMMON STOCK 039483102   172,794 1,861 SH   SOLE   172,794 0 0
ARCTOS NORTHSTAR ACQUISIT A COMMON STOCK USD.0001 G0477L100   1,513,500 150,000 SH   SOLE   1,513,500 0 0
ARCTOS NORTHSTAR ACQUISIT A ARCTOS NORTHSTAR ACQ CW28 G0477L126   1,586 37,500 SH   SOLE   1,586 0 0
ARES ACQUISITION CORP A COMMON STOCK USD.0001 G33032106   2,014,000 200,000 SH   SOLE   2,014,000 0 0
ARES ACQUISITION CORP A ARES ACQUISITION CL A CW27 G33032122   18,652 40,000 SH   SOLE   18,652 0 0
ARGO GROUP INTERNATIONAL COMMON STOCK USD1.0 G0464B107   195,891 7,578 SH   SOLE   195,891 0 0
ARISTA NETWORKS INC COMMON STOCK USD.0001 040413106   469,867 3,872 SH   SOLE   469,867 0 0
ARROWHEAD PHARMACEUTICALS IN COMMON STOCK USD.001 04280A100   106,511 2,626 SH   SOLE   106,511 0 0
ARTHUR J GALLAGHER CO COMMON STOCK USD1.0 363576109   98,795 524 SH   SOLE   98,795 0 0
ARYA SCIENCES ACQUISITION A COMMON STOCK USD.0001 G31658100   1,005,500 100,000 SH   SOLE   1,005,500 0 0
ASCENDANT DIGITAL ACQU CL A WARRANT G05157113   15,005 25,000 SH   SOLE   15,005 0 0
ASCENDANT DIGITAL ACQU CL A COMMON STOCK USD.0001 G05157105   516,000 50,000 SH   SOLE   516,000 0 0
ASCENDIS PHARMA A/S ADR ADR DKK1.0 04351P101   283,830 2,324 SH   SOLE   283,830 0 0
ASGN INC COMMON STOCK USD.01 00191U102   12,874 158 SH   SOLE   12,874 0 0
ASHLAND INC COMMON STOCK 044186104   364,097 3,386 SH   SOLE   364,097 0 0
ASPEN TECHNOLOGY INC COMMON STOCK 29109X106   580,050 2,824 SH   SOLE   580,050 0 0
ASSURANT INC COMMON STOCK USD.01 04621X108   29,264 234 SH   SOLE   29,264 0 0
AT T INC COMMON STOCK USD1.0 00206R102   319,561 17,358 SH   SOLE   319,561 0 0
ATHENA CONSUMER ACQUISITIO A ATHENA CONSUMER ACQ CW23 04684M114   2,908 25,000 SH   SOLE   2,908 0 0
ATKORE INC COMMON STOCK USD.01 047649108   1,407,429 12,409 SH   SOLE   1,407,429 0 0
ATLAS AIR WORLDWIDE HOLDINGS COMMON STOCK USD.01 049164205   4,092,480 40,600 SH   SOLE   4,092,480 0 0
ATMOS ENERGY CORP COMMON STOCK 049560105   6,948 62 SH   SOLE   6,948 0 0
AURINIA PHARMACEUTICALS INC COMMON STOCK 05156V102   24,754 5,730 SH   SOLE   24,754 0 0
AURORA ACQUISITION CORP A COMMON STOCK USD.0001 G0698L103   1,261,250 125,000 SH   SOLE   1,261,250 0 0
AURORA ACQUISITION CORP A AURORA ACQUISITION A CW28 G0698L129   469 31,250 SH   SOLE   469 0 0
AUTHENTIC EQUITY ACQUISITI A COMMON STOCK USD.0001 G06607108   252,875 25,000 SH   SOLE   252,875 0 0
AUTHENTIC EQUITY ACQUISITI A AUTHENTIC EQUITY ACQ CW27 G06607124   195 12,500 SH   SOLE   195 0 0
AUTODESK INC COMMON STOCK USD.01 052769106   1,272,211 6,808 SH   SOLE   1,272,211 0 0
AUTOHOME INC ADR ADR USD.01 05278C107   607,930 19,867 SH   SOLE   607,930 0 0
AUTOLIV INC COMMON STOCK USD1.0 052800109   94,423 1,233 SH   SOLE   94,423 0 0
AUTOMATIC DATA PROCESSING COMMON STOCK USD.1 053015103   490,380 2,053 SH   SOLE   490,380 0 0
AUTONATION INC COMMON STOCK USD.01 05329W102   769,341 7,170 SH   SOLE   769,341 0 0
AUTOZONE INC COMMON STOCK USD.01 053332102   4,286,221 1,738 SH   SOLE   4,286,221 0 0
AVALONBAY COMMUNITIES INC REIT USD.01 053484101   1,395,210 8,638 SH   SOLE   1,395,210 0 0
AVERY DENNISON CORP COMMON STOCK USD1.0 053611109   1,738,686 9,606 SH   SOLE   1,738,686 0 0
AVNET INC COMMON STOCK USD1.0 053807103   522,993 12,578 SH   SOLE   522,993 0 0
AXALTA COATING SYSTEMS LTD COMMON STOCK USD1.0 G0750C108   619,278 24,314 SH   SOLE   619,278 0 0
AXCELIS TECHNOLOGIES INC COMMON STOCK USD.001 054540208   567,741 7,154 SH   SOLE   567,741 0 0
AXIS CAPITAL HOLDINGS LTD COMMON STOCK USD.0125 G0692U109   960,759 17,736 SH   SOLE   960,759 0 0
AXONICS INC COMMON STOCK USD.0001 05465P101   223,232 3,570 SH   SOLE   223,232 0 0
BAKER HUGHES CO COMMON STOCK USD.0001 05722G100   77,546 2,626 SH   SOLE   77,546 0 0
BANK OF AMERICA CORP COMMON STOCK USD.01 060505104   31,989,283 965,860 SH   SOLE   31,989,283 0 0
BANK OF NEW YORK MELLON CORP COMMON STOCK USD.01 064058100   944,085 20,740 SH   SOLE   944,085 0 0
BANK OZK COMMON STOCK 06417N103   2,460,645 61,424 SH   SOLE   2,460,645 0 0
BATH BODY WORKS INC COMMON STOCK USD.5 070830104   490,636 11,643 SH   SOLE   490,636 0 0
BEARD ENERGY TRANSITION AC A COMMON STOCK USD.0001 07402Q101   1,528,500 150,000 SH   SOLE   1,528,500 0 0
BEARD ENERGY TRANSITION AC A BEARD ENERGY TRANSITIO CW27 07402Q119   4,875 75,000 SH   SOLE   4,875 0 0
BECTON DICKINSON AND CO COMMON STOCK USD1.0 075887109   224,801 884 SH   SOLE   224,801 0 0
BED BATH BEYOND INC COMMON STOCK USD.01 075896100   103,962 41,419 SH   SOLE   103,962 0 0
BENSON HILL INC WARRANT 082490111   1,876 7,500 SH   SOLE   1,876 0 0
BERKSHIRE GREY INC BERKSHIRE GREY CW26 084656115   1,858 30,961 SH   SOLE   1,858 0 0
BERKSHIRE HATHAWAY INC CL B COMMON STOCK USD.0033 084670702   39,509,855 127,905 SH   SOLE   39,509,855 0 0
BERRY GLOBAL GROUP INC COMMON STOCK USD.01 08579W103   264,321 4,374 SH   SOLE   264,321 0 0
BEST BUY CO INC COMMON STOCK USD.1 086516101   343,379 4,281 SH   SOLE   343,379 0 0
BILANDER ACQUISITION CORP A COMMON STOCK USD.0001 09001T106   1,978,000 200,000 SH   SOLE   1,978,000 0 0
BILANDER ACQUISITION CORP A BILANDER ACQ CL A CW27 09001T114   9,000 50,000 SH   SOLE   9,000 0 0
BILL.COM HOLDINGS INC COMMON STOCK USD.00001 090043100   10,024 92 SH   SOLE   10,024 0 0
BIO RAD LABORATORIES A COMMON STOCK USD.0001 090572207   66,858 159 SH   SOLE   66,858 0 0
BIO TECHNE CORP COMMON STOCK USD.01 09073M104   75,587 912 SH   SOLE   75,587 0 0
BIOGEN INC COMMON STOCK USD.0005 09062X103   635,531 2,295 SH   SOLE   635,531 0 0
BIOMARIN PHARMACEUTICAL INC COMMON STOCK USD.001 09061G101   53,504 517 SH   SOLE   53,504 0 0
BIOPLUS ACQUISITION CORP A COMMON STOCK USD.0001 G11217117   257,000 25,000 SH   SOLE   257,000 0 0
BIOPLUS ACQUISITION CORP A BIOPLUS ACQUISITION CW23 G11217125   575 12,500 SH   SOLE   575 0 0
BIOTE CORP A BIOTE CW27 090683111   2,155 7,000 SH   SOLE   2,155 0 0
BITE ACQUISITION CORP BITE ACQUISITION CORP CW27 09175K113   1,500 25,000 SH   SOLE   1,500 0 0
BJ S WHOLESALE CLUB HOLDINGS COMMON STOCK USD.01 05550J101   916,581 13,854 SH   SOLE   916,581 0 0
BLACKLINE INC COMMON STOCK USD.01 09239B109   117,857 1,752 SH   SOLE   117,857 0 0
BLACKROCK INC COMMON STOCK USD.01 09247X101   610,839 862 SH   SOLE   610,839 0 0
BLACKSTONE INC COMMON STOCK USD.00001 09260D107   1,320,359 17,797 SH   SOLE   1,320,359 0 0
BLACKSTONE MORTGAGE TRU CL A REIT USD.01 09257W100   990,142 46,771 SH   SOLE   990,142 0 0
BLEUACACIA LTD RIGHT G11728139   8,500 100,000 SH   SOLE   8,500 0 0
BLOOM ENERGY CORP A COMMON STOCK USD.0001 093712107   433,986 22,698 SH   SOLE   433,986 0 0
BLOOMIN BRANDS INC COMMON STOCK USD.01 094235108   231,058 11,484 SH   SOLE   231,058 0 0
BLUE OWL CAPITAL INC COMMON STOCK USD.0001 09581B103   742,413 70,039 SH   SOLE   742,413 0 0
BLUE WHALE ACQUISITION COR A COMMON STOCK USD.0001 G1330M103   979,000 100,000 SH   SOLE   979,000 0 0
BLUE WHALE ACQUISITION COR A BLUE WHALE ACQ CORP CW23 G1330M129   1,783 25,000 SH   SOLE   1,783 0 0
BLUEACACIA LTD CLASS A COMMON STOCK USD.0001 G11728105   1,004,000 100,000 SH   SOLE   1,004,000 0 0
BLUEACACIA LTD CLASS A BLUEACACIA LTD CL A CW23 G11728113   1,660 50,000 SH   SOLE   1,660 0 0
BLUERIVER ACQUISITION CORP UNIT USD.0001 G1261Q123   20 2 SH   SOLE   20 0 0
BLUERIVER ACQUISITION CORP A COMMON STOCK USD.0001 G1261Q107   201,780 19,998 SH   SOLE   201,780 0 0
BLUERIVER ACQUISITION CORP A BLUERIVER ACQUISIT A CW26 G1261Q115   106 6,666 SH   SOLE   106 0 0
BLUESCAPE OPPORTUNITIES AC A BLUESCAPE OPPORTUNIT A CW26 G1195N113   8,000 49,999 SH   SOLE   8,000 0 0
BLUESCAPE OPPORTUNITIES ACQ UNIT USD.0001 G1195N121   20 2 SH   SOLE   20 0 0
BOEING CO/THE COMMON STOCK USD5.0 097023105   128,200 673 SH   SOLE   128,200 0 0
BOK FINANCIAL CORPORATION COMMON STOCK USD.00006 05561Q201   1,400,438 13,493 SH   SOLE   1,400,438 0 0
BOOKING HOLDINGS INC COMMON STOCK USD.008 09857L108   12,599,531 6,252 SH   SOLE   12,599,531 0 0
BOOZ ALLEN HAMILTON HOLDINGS COMMON STOCK USD.01 099502106   3,445,084 32,961 SH   SOLE   3,445,084 0 0
BORGWARNER INC COMMON STOCK USD.01 099724106   86,699 2,154 SH   SOLE   86,699 0 0
BOSTON PROPERTIES INC REIT USD.01 101121101   848,197 12,551 SH   SOLE   848,197 0 0
BOSTON SCIENTIFIC CORP COMMON STOCK USD.01 101137107   4,111,228 88,853 SH   SOLE   4,111,228 0 0
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HP INC COMMON STOCK USD.01 40434L105   857,287 31,905 SH   SOLE   857,287 0 0
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IDEX CORP COMMON STOCK USD.01 45167R104   22,511,511 98,592 SH   SOLE   22,511,511 0 0
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ITT INC COMMON STOCK USD1.0 45073V108   1,543,739 19,035 SH   SOLE   1,543,739 0 0
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T ROWE PRICE GROUP INC COMMON STOCK USD.2 74144T108   169,697 1,556 SH   SOLE   169,697 0 0
TAILWIND ACQUISITION -CW27 WARRANT 87403Q110   1,750 25,000 SH   SOLE   1,750 0 0
TAILWIND INTERNATIONAL ACQ A WARRANT G8662F119   137 33,332 SH   SOLE   137 0 0
TAILWIND INTERNATIONAL ACQ A COMMON STOCK USD.0001 G8662F101   1,008,960 99,996 SH   SOLE   1,008,960 0 0
TAILWIND INTERNATIONAL ACQUI UNIT USD.0001 G8662F127   40 4 SH   SOLE   40 0 0
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TAPESTRY INC COMMON STOCK USD.01 876030107   2,326,193 61,087 SH   SOLE   2,326,193 0 0
TARGA RESOURCES CORP COMMON STOCK USD.001 87612G101   49,392 672 SH   SOLE   49,392 0 0
TARGET CORP COMMON STOCK USD.0833 87612E106   1,640,781 11,009 SH   SOLE   1,640,781 0 0
TARGET GLOBAL ACQUISITION A COMMON STOCK USD.0001 G8675N109   3,072,000 300,000 SH   SOLE   3,072,000 0 0
TARGET GLOBAL ACQUISITION A TARGET GLOBAL ACQ I CW27 G8675N125   13,030 100,000 SH   SOLE   13,030 0 0
TCV ACQUISITION CORP A COMMON STOCK USD.0001 G8704C124   558,530 55,300 SH   SOLE   558,530 0 0
TE CONNECTIVITY LTD COMMON STOCK CHF.57 H84989104   71,865 626 SH   SOLE   71,865 0 0
TECH AND ENERGY TRANSITION UNIT USD.0001 87823R201   21 2 SH   SOLE   21 0 0
TECH AND ENERGY TRANSITION A COMMON STOCK USD.0001 87823R102   1,253,730 124,998 SH   SOLE   1,253,730 0 0
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TEGNA INC COMMON STOCK USD1.0 87901J105   340,905 16,088 SH   SOLE   340,905 0 0
TELEDYNE TECHNOLOGIES INC COMMON STOCK USD.01 879360105   1,888,775 4,723 SH   SOLE   1,888,775 0 0
TELEFLEX INC COMMON STOCK USD1.0 879369106   114,081 457 SH   SOLE   114,081 0 0
TELOS CORPORATION COMMON STOCK USD.001 87969B101   116,948 22,976 SH   SOLE   116,948 0 0
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TENET HEALTHCARE CORP COMMON STOCK USD.05 88033G407   457,211 9,371 SH   SOLE   457,211 0 0
TERADATA CORP COMMON STOCK USD.01 88076W103   379,315 11,269 SH   SOLE   379,315 0 0
TERADYNE INC COMMON STOCK USD.125 880770102   220,471 2,524 SH   SOLE   220,471 0 0
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TESLA INC COMMON STOCK USD.001 88160R101   1,570,175 12,747 SH   SOLE   1,570,175 0 0
TEXAS INSTRUMENTS INC COMMON STOCK USD1.0 882508104   401,319 2,429 SH   SOLE   401,319 0 0
TEXAS ROADHOUSE INC COMMON STOCK USD.001 882681109   197,089 2,167 SH   SOLE   197,089 0 0
TEXTRON INC COMMON STOCK USD.125 883203101   571,568 8,073 SH   SOLE   571,568 0 0
TG THERAPEUTICS INC COMMON STOCK USD.001 88322Q108   223,457 18,889 SH   SOLE   223,457 0 0
TH INTERNATIONAL LTD/CAYMAN TH INTERNATIONAL LTD/CAYM 27 G8656L114   9,008 75,000 SH   SOLE   9,008 0 0
THERMO FISHER SCIENTIFIC INC COMMON STOCK USD1.0 883556102   5,204,021 9,450 SH   SOLE   5,204,021 0 0
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TIMKEN CO COMMON STOCK 887389104   1,449,936 20,517 SH   SOLE   1,449,936 0 0
TITAN MACHINERY INC COMMON STOCK USD.00001 88830R101   150,378 3,785 SH   SOLE   150,378 0 0
TJX COMPANIES INC COMMON STOCK USD1.0 872540109   19,307,458 242,556 SH   SOLE   19,307,458 0 0
TLG ACQUISITION ONE COR CL A WARRANT 87257M116   4,100 100,000 SH   SOLE   4,100 0 0
TOLL BROTHERS INC COMMON STOCK USD.01 889478103   299,470 5,999 SH   SOLE   299,470 0 0
TORO CO COMMON STOCK USD1.0 891092108   2,184,873 19,301 SH   SOLE   2,184,873 0 0
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TOWER SEMICONDUCTOR LTD COMMON STOCK ILS15.0 M87915274   274,450 6,353 SH   SOLE   274,450 0 0
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TPG RE FINANCE TRUST INC REIT USD.001 87266M107   118,540 17,458 SH   SOLE   118,540 0 0
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TRONOX HOLDINGS PLC COMMON STOCK USD.01 G9087Q102   130,218 9,498 SH   SOLE   130,218 0 0
TRUIST FINANCIAL CORP COMMON STOCK USD5.0 89832Q109   189,504 4,404 SH   SOLE   189,504 0 0
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