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Stock-Based Compensation (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2012
Share-based Compensation        
Plan Automatic Replenishment   1,200,000    
Fair value of vested awards $ 64.5 $ 56.8    
Unrecognized compensation expense $ 97.3      
Weighted-average period of unrecognized compensation expense (in years) 3 years      
2015 Inducement Plan [Member]        
Share-based Compensation        
Shares Available to Grant Under Plan 300,000      
2015 Equity Incentive Plan [Member]        
Share-based Compensation        
Shares Available to Grant Under Plan 1,400,000      
2006 Equity Incentive Plan        
Share-based Compensation        
Options expiration term 10 years      
Percentage of shares vesting one year after the options' vesting commencement date (in hundredths) 25.00%      
Plan automatic replenishment provision (in hundredths)   3.10% 3.30% 3.50%
1999 Stock Plan        
Share-based Compensation        
Percentage of fair value price options under the plan to be granted, minimum (in hundredths) 85.00%      
Percentage of fair value price options could be exercised on grant date, minimum (in hundredths) 100.00%      
Percentage of stockholders with applicable exercise price (in hundredths) 10.00%      
Percentage of exercise price of options granted to certain stockholders to fair value of shares on grant date (in hundredths) 110.00%      
Vesting period of restricted stock, minimum (in years) 4 years      
Tiny Prints 2008 Equity Plan        
Share-based Compensation        
Options expiration term 10 years      
Percentage of shares vesting one year after the options' vesting commencement date (in hundredths) 25.00%      
Max | 2006 Equity Incentive Plan        
Share-based Compensation        
Vesting period of restricted stock, minimum (in years) 3 years      
Max | Tiny Prints 2008 Equity Plan        
Share-based Compensation        
Vesting period of restricted stock, minimum (in years) 3 years      
Min | 2006 Equity Incentive Plan        
Share-based Compensation        
Vesting period of restricted stock, minimum (in years) 1 year      
Min | Tiny Prints 2008 Equity Plan        
Share-based Compensation        
Vesting period of restricted stock, minimum (in years) 1 year      
Restricted Stock Units (RSUs) | Max | 2006 Equity Incentive Plan        
Share-based Compensation        
Vesting period of restricted stock, minimum (in years) 4 years      
Restricted Stock Units (RSUs) | Min | 2006 Equity Incentive Plan        
Share-based Compensation        
Vesting period of restricted stock, minimum (in years) 3 years      
Performance shares | 2006 Equity Incentive Plan        
Share-based Compensation        
Vesting period of restricted stock, minimum (in years) 4 years      
Non-Qualified Stock Options | 1999 Stock Plan        
Share-based Compensation        
Options expiration term 10 years      
Incentive Stock Options | 1999 Stock Plan        
Share-based Compensation        
Options expiration term 5 years