SCHEDULE 13G/A 0001125725 XXXXXXXX LIVE 1 Common Stock 12/31/2025 0001217234 CareDx, Inc. 14167L103 8000 Marina Boulevard 4th Floor Brisbane CA 94005 Rule 13d-1(c) Gagnon Securities LLC b DE 0.00 1897611.00 0.00 2213827.00 2213827.00 N 4.3 BD IA Gagnon Advisors, LLC b DE 0.00 532892.00 0.00 532892.00 532892.00 N 1.0 IA Neil Gagnon b X1 177878.00 2551068.00 177878.00 2877068.00 3054946.00 N 5.9 IN CareDx, Inc. 8000 Marina Boulevard, 4th Floor, Brisbane, CA 94005 Neil Gagnon has sole voting and dispositive power over 177,878 shares of the Issuer's common stock, par value $0.001 per share (the "Common Stock"). In addition, Mr. Gagnon has shared voting power over 2,551,068 shares of Common Stock and shared dispositive power over 2,877,068 shares of Common Stock. Mr. Gagnon is the Chief Executive Officer and principal owner of Gagnon Securities LLC ("GS"), an investment adviser registered with the U.S. Securities and Exchange Commission ("SEC") under the Investment Advisers Act of 1940, as amended (the "Advisers Act"), and a registered broker-dealer, in its role as investment manager to several customer accounts, foundations, partnerships and trusts (collectively, the "Accounts") to which it furnishes investment advice. GS and Mr. Gagnon may be deemed to share voting power with respect to 1,897,611 shares of Common Stock held in the Accounts and dispositive power with respect to 2,213,827 shares of Common Stock held in the Accounts. GS and Mr. Gagnon expressly disclaim beneficial ownership of all securities held in the Accounts. Mr. Gagnon is also the managing member of Gagnon Advisors, LLC ("Gagnon Advisors"), an investment adviser registered with the SEC under the Advisers Act. Mr. Gagnon and Gagnon Advisors, in its role as investment manager to Gagnon Investment Associates, LLC ("GIA"), a private investment fund, may be deemed to share voting and dispositive power with respect to the 532,892 shares of Common Stock held by GIA. Gagnon Advisors and Mr. Gagnon expressly disclaim beneficial ownership of all securities held by GIA. 1370 Ave. of Americas, 26th Floor, New York, NY 10019 Gagnon Securities LLC Delaware limited liability company Gagnon Advisors, LLC Delaware limited liability company Neil Gagnon USA Y Gagnon Securities LLC 2,213,827 Gagnon Advisors, LLC 532,892 Neil Gagnon 3,054,946 Gagnon Securities LLC 4.3% Gagnon Advisors, LLC 1.0% Neil Gagnon 5.9% Gagnon Securities LLC 0 Gagnon Advisors, LLC 0 Neil Gagnon 177,878 Gagnon Securities LLC 1,897,611 Gagnon Advisors, LLC 532,892 Neil Gagnon 2,551,068 Gagnon Securities LLC 0 Gagnon Advisors, LLC 0 Neil Gagnon 177,878 Gagnon Securities LLC 2,213,827 Gagnon Advisors, LLC 532,892 Neil Gagnon 2,877,068 N The Accounts described above in Item 2 have the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, securities held in their respective accounts. To the knowledge of the Reporting Persons, the interest in any such account does not exceed 5% of the class of securities. Except to the extent described herein, the Reporting Person disclaims beneficial ownership of all such securities. Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. Gagnon Securities LLC /s/ Neil Gagnon 02/12/2026 Gagnon Advisors, LLC /s/ Neil Gagnon 02/12/2026 Neil Gagnon /s/ Neil Gagnon 02/12/2026