X0407 4 2023-03-22 0 0001124524 Cryoport, Inc. CYRX 0001283212 SHELTON JERRELL C/O CRYOPORT INC. 112 WESTWOOD PLACE, SUITE 350 BRENTWOOD TN 37027 1 1 0 0 Chief Executive Officer 0 Common Stock 2023-03-22 4 A 0 27092 0 A 460081 D Stock Option (right to buy) 23.78 2023-03-22 4 A 0 60952 0 A 2030-03-22 Common Stock 60952 60952 D Represents restricted stock rights, which are a contingent right to receive one share of CYRX common stock, that vest in four equal annual installments beginning 3/22/2024. 1/48 of options vest on the 22nd of each month for forty-eight months beginning 4/22/2023. /s/ Jerrell Shelton 2023-03-24