MAYO LICENSE AGREEMENT (Details) $ in Thousands	1 Months Ended		3 Months Ended				6 Months Ended
	Dec. 31, 2016 USD ($)	Jan. 31, 2016 USD ($)	Jun. 30, 2017 USD ($)	Jun. 30, 2016 USD ($)	Mar. 31, 2016 USD ($)	Mar. 31, 2015 USD ($)	Jun. 30, 2017 USD ($)	Jun. 30, 2016 USD ($)	Feb. 28, 2015 USD ($) installment
Other Payments
Charges incurred as part of the research collaboration			$ 9,737	$ 8,640			$ 17,739	$ 18,766
Licensing Agreements | MAYO
Other Payments
Charges incurred as part of the research collaboration			1,100	800			2,200	1,800
Payments for research and development efforts			500	1,300			1,800	2,400
Estimated liability for research and development efforts			$ 1,200	$ 700			$ 1,200	700
Amendments
License fees payable in five annual installments									$ 5,000
License fee payments	$ 1,000				$ 1,000	$ 1,000
Number of annual installments in which license fees are payable | installment									5
Number of periods each installment is amortized over							12 months
Amortization of installments							$ 300	$ 500
Licensing Agreements | MAYO | Sales Milestone Range One
Warrants
Amount agreed to be paid upon reaching the specified amount of net sales		$ 200
Net sales of a licensed product		5,000
Licensing Agreements | MAYO | Sales Milestone Range Two
Warrants
Amount agreed to be paid upon reaching the specified amount of net sales		800
Net sales of a licensed product		20,000
Licensing Agreements | MAYO | Sales Milestone Range Three
Warrants
Amount agreed to be paid upon reaching the specified amount of net sales		2,000
Net sales of a licensed product		$ 50,000
Licensing Agreements | MAYO | Minimum
Warrants
Royalty payments							$ 25