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MAYO LICENSE AGREEMENT (Details)
$ in Thousands
1 Months Ended 3 Months Ended
Jan. 31, 2016
USD ($)
Mar. 31, 2017
USD ($)
Mar. 31, 2016
USD ($)
Mar. 31, 2015
USD ($)
Feb. 28, 2015
USD ($)
installment
Other Payments          
Charges incurred as part of the research collaboration   $ 8,002 $ 10,126    
Licensing Agreements | MAYO          
Other Payments          
Charges incurred as part of the research collaboration   1,100 1,000    
Payments for research and development efforts   1,400 1,000    
Estimated liability for research and development efforts   600 1,200    
Amendments          
License fees payable in five annual installments         $ 5,000
License fee payments     $ 1,000 $ 1,000  
Number of annual installments in which license fees are payable | installment         5
Licensing Agreements | MAYO | Sales Milestone Range One          
Warrants          
Amount agreed to be paid upon reaching the specified amount of net sales $ 200        
Net sales of a licensed product 5,000        
Licensing Agreements | MAYO | Sales Milestone Range Two          
Warrants          
Amount agreed to be paid upon reaching the specified amount of net sales 800        
Net sales of a licensed product 20,000        
Licensing Agreements | MAYO | Sales Milestone Range Three          
Warrants          
Amount agreed to be paid upon reaching the specified amount of net sales 2,000        
Net sales of a licensed product $ 50,000        
Licensing Agreements | MAYO | Minimum          
Warrants          
Royalty payments   $ 25