SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables)

3 Months Ended

Mar. 31, 2017

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Schedule of available-for-sale securities

Available-for-sale securities at March 31, 2017 consisted of the following:

	March 31, 2017
			Gains in Accumulated		Losses in Accumulated
			Other Comprehensive		Other Comprehensive		Estimated Fair
(In thousands)	Amortized Cost		Income		Income		Value
Corporate bonds	$	110,463	$	13	$	(79)	$	110,397
Asset backed securities		54,274		2		(35)		54,241
U.S. government agency securities		49,586		—		(123)		49,463
Commercial paper		17,108		2		—		17,110
Certificates of deposit		4,252		1		—		4,253
Total available-for-sale securities	$	235,683	$	18	$	(237)	$	235,464

Available-for-sale securities at December 31, 2016 consisted of the following:

	December 31, 2016
			Gains in Accumulated		Losses in Accumulated
			Other Comprehensive		Other Comprehensive		Estimated Fair
(In thousands)	Amortized Cost		Income		Income		Value
Corporate bonds	$	137,013	$	17	$	(93)	$	136,937
Asset backed securities		55,667		3		(30)		55,640
U.S. government agency securities		49,591		3		(120)		49,474
Commercial paper		19,069		8		(1)		19,076
Certificates of deposit		1,053		—		(1)		1,052
Total available-for-sale securities	$	262,393	$	31	$	(245)	$	262,179

Schedule of amounts recognized in accumulated other comprehensive income (loss) (AOCI)

The amounts recognized in accumulated other comprehensive income (loss) (“AOCI”) for the three months ended March 31, 2017 were as follows:

					Accumulated
	Cumulative		Unrealized		Other
	Translation		Gain (Loss)		Comprehensive
(In thousands)	Adjustment		on Securities		Income (Loss)
Balance at December 31, 2016	$	(204)	$	(214)	$	(418)
Other comprehensive loss before reclassifications		(8)		(3)		(11)
Amounts reclassified from accumulated other comprehensive loss		—		(2)		(2)
Net current period change in accumulated other comprehensive loss		(8)		(5)		(13)
Balance at March 31, 2017	$	(212)	$	(219)	$	(431)

The amounts recognized in AOCI for the three months ended March 31, 2016 were as follows:

					Accumulated
	Cumulative		Unrealized		Other
	Translation		Gain (Loss)		Comprehensive
(In thousands)	Adjustment		on Securities		Income (Loss)
Balance at December 31, 2015	$	11	$	(444)	$	(433)
Other comprehensive (loss) income before reclassifications		(57)		456		399
Amounts reclassified from accumulated other comprehensive loss		—		17		17
Net current period change in accumulated other comprehensive (loss) income		(57)		473		416
Balance at March 31, 2016	$	(46)	$	29	$	(17)

Schedule of amounts reclassified from accumulated other comprehensive income (loss)

Amounts reclassified from AOCI for the three months ended March 31, 2017 and 2016 were as follows:

	Affected Line Item in the	Three Months Ended March 31,
Details about AOCI  Components (In thousands)	Statement of Operations	2017		2016
Change in value of available-for-sale investments
Sales and maturities of available-for-sale investments	Investment income	$	(2)	$	17
Total reclassifications		$	(2)	$	17

Schedule of estimated useful lives of fixed assets

	Estimated
Asset Classification	Useful Life
Laboratory equipment	3 - 5 years
Computer equipment and computer software	3 years
Leasehold improvements	Lesser of the remaining lease term or useful life
Building Improvements	Lesser of the remaining building life or useful life
Furniture and fixtures	3 years
Buildings	30 years

Schedule of potentially issuable common shares not included in the computation of diluted net loss per share because they would have an anti-dilutive effect

	March 31,
(In thousands)	2017	2016
Shares issuable upon exercise of stock options	3,613	5,475
Shares issuable upon the release of restricted stock awards	5,553	6,202
	9,166	11,677

Schedule of components of revenue

	Three Months Ended March 31,
(In thousands)	2017		2016
Revenue recognized on an accrual basis	$	43,854	$	13,676
Revenue recognized when cash is received		4,509		1,159
Total	$	48,363	$	14,835

Schedule of inventory

Inventory consists of the following:

	March 31,		December 31,
(In thousands)	2017		2016
Raw materials	$	2,754	$	2,408
Semi-finished and finished goods		5,105		4,425
Total inventory	$	7,859	$	6,833