Condensed Consolidated Balance Sheets - USD ($) $ in Thousands	Sep. 30, 2016	Dec. 31, 2015
Current Assets:
Cash and cash equivalents	$ 63,445	$ 41,135
Marketable securities	274,385	265,744
Accounts receivable, net	7,863	4,933
Inventory, net	7,666	6,677
Prepaid expenses and other current assets	5,673	7,375
Total current assets	359,032	325,864
Property and Equipment, at cost:
Computer equipment and computer software	19,053	14,025
Laboratory equipment	14,249	12,786
Leasehold improvements	13,308	7,118
Assets under construction	6,536	8,038
Buildings	4,792	4,777
Furniture and fixtures	2,515	1,265
Property and Equipment, gross	60,453	48,009
Less-Accumulated depreciation	(21,980)	(13,913)
Net property and equipment	38,473	34,096
Other long-term assets	5,706	4,070
Total assets	403,211	364,030
Current Liabilities:
Accounts payable	2,335	3,308
Accrued liabilities	26,104	22,253
Debt and capital lease obligation, current portion	172	166
Other short-term liabilities	1,450	996
Total current liabilities	30,061	26,723
Long-term debt	4,673	4,789
Other long-term liabilities	5,308	4,601
Lease incentive obligation, less current portion	840	1,061
Total liabilities	40,882	37,174
Commitments and contingencies
Stockholders' Equity:
Preferred stock, $0.01 par value Authorized—5,000,000 shares issued and outstanding—no shares at September 30, 2016 and December 31, 2015
Common stock, $0.01 par value Authorized—200,000,000 shares issued and outstanding—108,410,279 and 96,674,786 shares at September 30, 2016 and December 31, 2015	1,084	967
Additional paid-in capital	1,070,083	904,932
Accumulated other comprehensive loss	(187)	(433)
Accumulated deficit	(708,651)	(578,610)
Total stockholders' equity	362,329	326,856
Total liabilities and stockholders’ equity	$ 403,211	$ 364,030