MAYO LICENSE AGREEMENT (Details) - USD ($)	1 Months Ended	3 Months Ended				6 Months Ended
	Jan. 31, 2016	Jun. 30, 2016	Mar. 31, 2016	Jun. 30, 2015	Mar. 31, 2015	Jun. 30, 2016	Jun. 30, 2015	Feb. 28, 2015
Other Payments
Charges incurred as part of the research collaboration		$ 8,640,000		$ 8,115,000		$ 18,766,000	$ 14,686,000
Licensing Agreements | MAYO
Warrants
Value of common stock required to be issued upon commercial launch of second and third products	$ 200,000
Other Payments
Charges incurred as part of the research collaboration		800,000		500,000		1,800,000	1,100,000
Payments for research and development efforts		1,300,000		400,000		2,400,000	1,600,000
Estimated liability for research and development efforts		$ 700,000		$ 700,000		700,000	$ 700,000
Amendments
License fees payable in five annual installments								$ 5,000,000
License fee payments			$ 1,000,000		$ 1,000,000
Licensing Agreements | MAYO | Sales Milestone Range One
Warrants
Amount agreed to be paid upon reaching the specified amount of net sales	200,000
Net sales of a licensed product	5,000,000
Licensing Agreements | MAYO | Sales Milestone Range Two
Warrants
Amount agreed to be paid upon reaching the specified amount of net sales	750,000
Net sales of a licensed product	20,000,000
Licensing Agreements | MAYO | Sales Milestone Range Three
Warrants
Amount agreed to be paid upon reaching the specified amount of net sales	2,000,000
Net sales of a licensed product	$ 50,000,000
Licensing Agreements | MAYO | Minimum
Warrants
Royalty payments						$ 25,000