SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES (Tables)

3 Months Ended

Mar. 31, 2016

SUMMARY OF SIGNIFICANT ACCOUNTING POLICIES

Schedule of available-for-sale securities

Available-for-sale securities at March 31, 2016 consisted of the following:

	March 31, 2016
			Gains in Accumulated		Losses in Accumulated
			Other Comprehensive		Other Comprehensive		Estimated Fair
(In thousands)	Amortized Cost		Income		Income		Value
Corporate bonds	$	132,854	$	93	$	(41)	$	132,906
Asset backed securities		62,380		12		(44)		62,348
U.S. government agency securities		7,057		8		—		7,065
Certificates of deposit		5,500		2		—		5,502
Commercial paper		2,621		—		(1)		2,620
Total available-for-sale securities	$	210,412	$	115	$	(86)	$	210,441

Available-for-sale securities at December 31, 2015 consisted of the following:

	December 31, 2015
			Gains in Accumulated		Losses in Accumulated
			Other Comprehensive		Other Comprehensive		Estimated Fair
(In thousands)	Amortized Cost		Income		Income		Value
Corporate bonds	$	179,471	$	2	$	(262)	$	179,211
Asset backed securities		77,661		—		(166)		77,495
U.S. government agency securities		7,057		—		(18)		7,039
Certificates of deposit		1,999		—		—		1,999
Total available-for-sale securities	$	266,188	$	2	$	(446)	$	265,744

Schedule of amounts recognized in accumulated other comprehensive income (loss) (AOCI)

The amounts recognized in accumulated other comprehensive income (loss) (“AOCI”) for the three months ended March 31, 2016 were as follows (in thousands):

					Accumulated
	Cumulative		Unrealized		Other
	Translation		Gain (Loss)		Comprehensive
	Adjustment		on Securities		Income (Loss)
Balance at December 31, 2015	$	11	$	(444)	$	(433)
Other comprehensive (loss) income before reclassifications		(57)		456		399
Amounts reclassified from accumulated other comprehensive loss		—		17		17
Net current period change in accumulated other comprehensive income (loss)		(57)		473		416
Balance at March 31, 2016	$	(46)	$	29	$	(17)

The amounts recognized in AOCI for the three months ended March 31, 2015 were as follows (in thousands):

					Accumulated
	Cumulative		Unrealized		Other
	Translation		Gain (Loss)		Comprehensive
	Adjustment		on Securities		Income (Loss)
Balance at December 31, 2014	$	—	$	(115)	$	(115)
Other comprehensive (loss) income before reclassifications		(10)		192		182
Amounts reclassified from accumulated other comprehensive loss		—		3		3
Net current period change in accumulated other comprehensive income (loss)		(10)		195		185
Balance at March 31, 2015	$	(10)	$	80	$	70

Schedule of amounts reclassified from accumulated other comprehensive income (loss)

Amounts reclassified from AOCI for the three months ended March 31, 2016 and 2015 were as follows (in thousands):

	Affected Line Item in the	Three Months Ended March 31,
Details about AOCI  Components	Statement of Operations	2016		2015
Change in value of available-for-sale investments
Sales and maturities of available-for-sale investments	Investment income	$	17	$	3
Total reclassifications		$	17	$	3

Schedule of estimated useful lives of fixed assets

	Estimated
Asset Classification	Useful Life
Laboratory equipment	3 - 5 years
Computer equipment and computer software	3 years
Leasehold improvements	Lesser of the remaining lease term or useful life
Furniture and fixtures	3 years
Buildings	30 years

Schedule of potentially issuable common shares not included in the computation of diluted net loss per share because they would have an anti-dilutive effect

	March 31,
	2016	2015
Shares issuable upon exercise of stock options	5,475	5,222
Shares issuable upon the release of restricted stock awards	6,202	2,305
Shares issuable upon the vesting of restricted stock awards related to licensing agreement	—	24
	11,677	7,551

Schedule of inventory

Inventory consists of the following (amount in thousands):

	March 31,		March 31,
	2016		2015
Raw materials	$	2,066	$	2,305
Semi-finished and finished goods		6,091		3,118
Total inventory	$	8,157	$	5,423