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COMMITMENTS AND CONTINGENCIES - Licensing Agreements (Details) - USD ($)
1 Months Ended 3 Months Ended 12 Months Ended
Jul. 24, 2015
Dec. 16, 2014
Apr. 02, 2014
Jun. 21, 2013
Jul. 26, 2010
Aug. 31, 2014
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Dec. 31, 2009
Commitments and contingencies                                    
Number of shares of common stock covered by warrants                                   75,000
Number of shares of restricted stock granted as a consideration for the expanded license 7,000,000 4,000,000 11,500,000 6,300,000                            
Research and development expense             $ 9,365,000 $ 9,863,000 $ 8,115,000 $ 6,571,000 $ 4,992,000 $ 9,073,000 $ 7,174,000 $ 7,430,000 $ 33,914,000 $ 28,669,000 $ 27,678,000  
Licensing Agreements | Hologic                                    
Commitments and contingencies                                    
Milestone payment contingent upon FDA approval           $ 100,000                        
Licensing Agreements | MDx Health                                    
Commitments and contingencies                                    
Minimum royalty fee that the entity is required to pay on each anniversary         $ 100,000                          
Amount agreed to be paid upon the first commercial sale of a licensed product         100,000                          
Licensing Agreements | MDx Health | Sales Milestone Range One                                    
Commitments and contingencies                                    
Amount agreed to be paid upon reaching the specified amount of net sales         150,000                          
Net sales of a licensed product         10,000,000                          
Licensing Agreements | MDx Health | Sales Milestone Range Two                                    
Commitments and contingencies                                    
Amount agreed to be paid upon reaching the specified amount of net sales         750,000                          
Net sales of a licensed product         50,000,000                          
Licensing Agreements | MDx Health | Sales Milestone Range Three                                    
Commitments and contingencies                                    
Amount agreed to be paid upon reaching the specified amount of net sales         1,000,000                          
Net sales of a licensed product         $ 50,000,000