Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Revenue
Laboratory service revenue	$ 39,437	$ 1,504
License fees		294	$ 4,144
Total revenue	39,437	1,798	4,144
Cost of sales	24,501	4,325
Gross margin	14,936	(2,527)	4,144
Operating expenses:
Research and development	33,914	28,669	27,678
General and administrative	57,950	30,435	13,649
Sales and marketing	82,140	38,908	9,578
Total operating expenses	174,004	98,012	50,905
Loss from operations	(159,068)	(100,539)	(46,761)
Other income (expense)
Investment income	1,271	542	316
Interest (expense)	(6)	(51)	(69)
Total other income	1,265	491	247
Net loss	$ (157,803)	$ (100,048)	$ (46,514)
Net loss per share-basic and diluted (in dollars per share)	$ (1.71)	$ (1.25)	$ (0.69)
Weighted average common shares outstanding-basic and diluted (in shares)	92,135	80,232	67,493