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Condensed Consolidated Statements of Cash Flows - USD ($)
9 Months Ended
Sep. 30, 2020
Sep. 30, 2019
Cash flows from operating activities:    
Net loss $ (411,723,000) $ (161,966,000)
Adjustments to reconcile net loss to net cash used in operating activities:    
Depreciation and amortization 53,345,000 21,920,000
Loss on disposal of property, plant and equipment 930,000 880,000
Unrealized gain on equity investments (1,183,000) 0
Deferred tax benefit (7,976,000) (341,000)
Stock-based compensation 111,075,000 60,657,000
Loss on settlement of convertible notes 7,954,000 10,558,000
Amortization of convertible note debt discount and issuance costs 55,222,000 30,778,000
Amortization of deferred financing costs and other liabilities (3,614,000) (2,421,000)
Amortization of premium on short-term investments 1,040,000 (6,229,000)
Amortization of acquired intangible assets 70,199,000 2,256,000
Intangible asset impairment charge 209,666,000 0
Non-cash lease expense 11,041,000 2,681,000
Changes in assets and liabilities:    
Accounts receivable, net (73,642,000) (36,871,000)
Inventory, net (18,472,000) (14,525,000)
Operating lease liabilities (6,135,000) (2,628,000)
Accounts payable and accrued liabilities (7,608,000) 16,279,000
Other assets and liabilities 34,959,000 (7,382,000)
Net cash provided by (used in) operating activities 25,078,000 (86,354,000)
Cash flows from investing activities:    
Purchases of marketable securities (890,012,000) (604,129,000)
Maturities and sales of marketable securities 559,907,000 1,449,330,000
Purchases of property, plant and equipment (47,782,000) (130,970,000)
Business combination, net of cash acquired (6,658,000) 0
Investments in privately held companies (10,610,000) 0
Other investing activities (244,000) (530,000)
Net cash provided by (used in) investing activities (395,399,000) 713,701,000
Cash flows from financing activities:    
Proceeds from issuance of convertible notes, net 1,125,547,000 729,477,000
Proceeds from exercise of common stock options 15,408,000 6,389,000
Proceeds in connection with the Company’s employee stock purchase plan 9,799,000 4,137,000
Payments on settlement of convertible notes (150,054,000) (493,356,000)
Other financing activities (938,000) (90,000)
Net cash provided by financing activities 999,762,000 246,557,000
Net increase in cash, cash equivalents and restricted cash 629,441,000 873,904,000
Cash and cash equivalents, beginning of period 177,528,000 160,430,000
Cash and cash equivalents, end of period 806,969,000 1,034,334,000
Supplemental disclosure of non-cash investing and financing activities:    
Property, plant and equipment acquired but not paid 7,209,000 16,933,000
Unrealized gain on available-for-sale investments, before tax 1,159,000 1,431,000
Issuance of 136,559 and 86,535 shares of common stock to fund the Company’s 401(k) matching contribution for 2019 and 2018, respectively 12,007,000 7,409,000
Issuance of 2,159,017 shares of common stock upon settlement of convertible notes 0 182,435,000
Retirement of equity component of convertible notes settled (64,199,000) (300,768,000)
Issuance of common stock for business combinations 28,847,000 0
Supplemental disclosure of cash flow information:    
Interest paid $ 9,239,000 $ 4,944,000