Statements of Operations (USD $) In Thousands, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2009
Revenue:
Product royalty fees	$ 20	$ 26	$ 25
License fees	4,143	5,318	4,733
Total revenue	4,163	5,344	4,758
Cost of revenue:
Product royalty fees	24	24	20
Gross profit	4,139	5,320	4,738
Operating expenses:
Research and development	21,968	9,023	4,213
General and administrative	8,137	6,330	9,549
Sales and marketing	2,857	1,793	226
Restructuring			(3)
Total operating expenses	32,962	17,146	13,985
Loss from operations	(28,823)	(11,826)	(9,247)
Interest income	169	46	120
Interest expense	(21)	(20)	(1)
Other income		244
Net loss	$ (28,675)	$ (11,556)	$ (9,128)
Net loss per share-basic and diluted (in dollars per share)	$ (0.54)	$ (0.29)	$ (0.28)
Weighted average common shares outstanding-basic (in shares)	52,512	40,455	32,791
Weighted average common shares outstanding-diluted (in shares)	52,512	40,455	32,791