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Related Parties - Additional Information (Detail) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
May 08, 2020
Sep. 30, 2020
Sep. 30, 2019
Sep. 30, 2020
Sep. 30, 2019
Jan. 10, 2020
Mosaic            
Related Party Transaction [Line Items]            
Expenses related to collaboration $ 0.8          
Payment related to collaboration       $ 3.0    
Mosaic | Maximum            
Related Party Transaction [Line Items]            
Milestone payments , clinical development events       4.0    
Mosaic | Research and development            
Related Party Transaction [Line Items]            
Cash research and development expense       0.8    
Mosaic | Collaboration Agreement | Intravitreal Anti-Complement Factor 3            
Related Party Transaction [Line Items]            
Expenses related to collaboration   $ 0.2 $ 0.3 $ 1.5 $ 0.8  
Biogen | License and Collaboration Agreement (the “Biogen Agreement”)            
Related Party Transaction [Line Items]            
Upfront license fee received from collaboration agreement           $ 15.0