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Nature of Operations - Additional Information (Detail)
$ in Thousands
12 Months Ended
Dec. 31, 2017
USD ($)
Segment
Dec. 31, 2016
USD ($)
Accounting Policies [Abstract]    
Number of operating segment | Segment 1  
Accumulated deficit $ 173,494 $ 147,982
Cash, cash equivalents and short-term investments 32,400  
Net loss 21,561 16,945
Cash used in operations $ 19,940 $ 18,472