X0609 4 2026-06-08 0001124105 GYRE THERAPEUTICS, INC. GYRE 0001959160 Luo Ying false C/O GYRE THERAPEUTICS, INC. 12730 HIGH BLUFF DRIVE, SUITE 250 SAN DIEGO CA 92130 true true Chief Executive Officer false Stock Option (Right to Buy) 6.05 2026-06-08 4 A 0 120000 0 A 2036-06-08 Common Stock 120000 120000 D This option represents a right to purchase a total of 120,000 shares of the Issuer's common stock, 25% of which will vest on June 8, 2027, with the remaining vesting in equal monthly installments over the following three years, subject to the Reporting Person's continued service to the Issuer through each vesting date. /s/ Thomas Eastling, as attorney-in-fact for Ying Luo 2026-06-10