X0306 4 2017-02-07 0 0001123494 HARVARD BIOSCIENCE INC HBIO 0001008643 GREEN DAVID 84 OCTOBER HILL ROAD HOLLISTON MA 01746 1 0 0 0 Common Stock 2017-02-07 4 S 0 3239 3.25 D 925571 D Common Stock 234896 I David Green 2015-1 Annuity Trust The sales reported in this Form 4 were effected pursuant to a Rule 10b5-1 trading plan adopted by the reporting person on June 1, 2016. Includes (a) a deferred stock award of 12,600 restricted stock units which vest quarterly in equal installments on March 31, 2017, June 30, 2017, September 30, 2017 and December 31, 2017; (b) a deferred stock award of 25,300 restricted stock units which fully vest on the earlier of (i) the date of the Issuer's next Annual Meeting of Stockholders after July 1, 2016, immediately prior to the commencement of such meeting, and (ii) July 1, 2017; and (c) 887,671 shares of common stock held by the Reporting Person. The reported sales were made pursuant to the terms of a 10b5-1 trading plan. This form has been signed under power of attorney. /s/ Chad Porter, by power of attorney 2017-02-10