X0202 4 2002-09-28 0 0001121702 METABOLIX, INC. MBLX 0001057677 GILES EDWARD M C/O METABOLIX, INC. 21 ERIE STREET CAMBRIDGE MA 02139 1 0 0 0 Common Stock 2007-09-28 4 S 0 100 25.25 D 144229 I By Giles Family Trust Common Stock 2002-09-28 4 S 0 1712 25.65 D 142517 I By Giles Family Trust Common Stock 374162 D Common Stock 97070 I By Isles Capital, L.P. Common Stock 105300 I By Metabolix 2006 GRAT I Common Stock 122593 I By Metabolix 2006 GRAT II Common Stock 1540 I By Robin Walter Giles Trust Common Stock 1540 I By Elizabeth Hartigan Giles Trust Transaction effected pursuant to a Rule 10b5-1 trading plan estabished by the reporting person on 9/14/07. The reporting person disclaims beneficial ownership except to the extent of his pecuniary interest, if any. /s/ Sarah P. Cecil, attorney-in-fact 2007-10-02